Necroptosis mediates the antineoplastic effects of the soluble fraction of polysaccharide from red wine in Walker-256 tumor-bearing rats.

Stipp, Maria Carolina; Bezerra, Iglesias de Lacerda; Corso, Claudia Rita; Dos Reis Livero, Francislaine A; Lomba, Luiz Alexandre; Caillot, Adriana Rute Cordeiro; Zampronio, Aleksander Roberto; Queiroz-Telles, José Ederaldo; Klassen, Giseli; Ramos, Edneia A S; Sassaki, Guilherme Lanzi; Acco, Alexandra

Stipp, Maria Carolina; Bezerra, Iglesias de Lacerda; Corso, Claudia Rita; Dos Reis Livero, Francislaine A; Lomba, Luiz Alexandre; Caillot, Adriana Rute Cordeiro; Zampronio, Aleksander Roberto; Queiroz-Telles, José Ederaldo; Klassen, Giseli; Ramos, Edneia A S; Sassaki, Guilherme Lanzi; Acco, Alexandra.

Afiliação

Stipp MC; Department of Pharmacology, Federal University of Paraná, Curitiba, PR, Brazil.
Bezerra IL; Department of Biochemistry and Molecular Biology, Federal University of Paraná, Curitiba, PR, Brazil.
Corso CR; Department of Pharmacology, Federal University of Paraná, Curitiba, PR, Brazil.
Dos Reis Livero FA; Department of Pharmacology, Federal University of Paraná, Curitiba, PR, Brazil.
Lomba LA; Department of Pharmacology, Federal University of Paraná, Curitiba, PR, Brazil.
Caillot AR; Department of Biochemistry and Molecular Biology, Federal University of Paraná, Curitiba, PR, Brazil.
Zampronio AR; Department of Pharmacology, Federal University of Paraná, Curitiba, PR, Brazil.
Queiroz-Telles JE; Department of Medical Pathology, Federal University of Paraná, Curitiba, PR, Brazil.
Klassen G; Department of Basic Pathology, Federal University of Paraná, Curitiba, PR, Brazil.
Ramos EA; Department of Basic Pathology, Federal University of Paraná, Curitiba, PR, Brazil.
Sassaki GL; Department of Biochemistry and Molecular Biology, Federal University of Paraná, Curitiba, PR, Brazil.
Acco A; Department of Pharmacology, Federal University of Paraná, Curitiba, PR, Brazil. Electronic address: aleacco@ufpr.br.

Carbohydr Polym ; 160: 123-133, 2017 Mar 15.

Article em En | MEDLINE | ID: mdl-28115086

Assuntos

Antineoplásicos/farmacologia; Apoptose; Neoplasias Experimentais/tratamento farmacológico; Polissacarídeos/farmacologia; Vinho; Animais; Antineoplásicos/química; Polissacarídeos/química; Proteínas Serina-Treonina Quinases/metabolismo; Ratos; Proteína Serina-Treonina Quinases de Interação com Receptores/metabolismo; Fator de Necrose Tumoral alfa/metabolismo

Palavras-chave

Griess solution (0.1% N-1-naphthyl-tilediamine, 1% sulfanilamide in 5% H(3)PO(4)); N-acetyl-ß-d-glucosamine; TriZol Reagent; Walker-256 tumor; buffered 10% formalin; cabernet franc; dimethylformamide 8%; eTrypan blue, 2 M trifluoroacetic acid; ethanol; ethylenediaminetetraacetic acid (EDTA) (0.5 M, pH 8.0); hematoxylin and eosin (HE); immunomodulation; ketamine hydrochloride; metothrexate; necroptosis; p-nitrofen; p-nitrophenyl-N-acetyl-ß-d-glucosamine; paraffin; phosphate buffer (pH 6.5); phosphate buffered saline (PBS, 16.5 mM phosphate, 137 mM NaCl, and 2.7 mM KCl) at pH 7.4; polysaccharide; red wine; saline Triton X-100 0.1%, TMB 18.4 mM; sodium acetate (NaOAc); xylazine hydrochloride;; xylol

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polissacarídeos / Vinho / Apoptose / Neoplasias Experimentais / Antineoplásicos Limite: Animals Idioma: En Revista: Carbohydr Polym Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Brasil

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