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Decreased STARD10 Expression Is Associated with Defective Insulin Secretion in Humans and Mice.
Carrat, Gaelle R; Hu, Ming; Nguyen-Tu, Marie-Sophie; Chabosseau, Pauline; Gaulton, Kyle J; van de Bunt, Martijn; Siddiq, Afshan; Falchi, Mario; Thurner, Matthias; Canouil, Mickaël; Pattou, Francois; Leclerc, Isabelle; Pullen, Timothy J; Cane, Matthew C; Prabhala, Priyanka; Greenwald, William; Schulte, Anke; Marchetti, Piero; Ibberson, Mark; MacDonald, Patrick E; Manning Fox, Jocelyn E; Gloyn, Anna L; Froguel, Philippe; Solimena, Michele; McCarthy, Mark I; Rutter, Guy A.
Afiliação
  • Carrat GR; Section of Cell Biology and Functional Genomics, Department of Medicine, Imperial College London, Hammersmith Hospital, du Cane Road, London W12 0NN, UK.
  • Hu M; Section of Cell Biology and Functional Genomics, Department of Medicine, Imperial College London, Hammersmith Hospital, du Cane Road, London W12 0NN, UK.
  • Nguyen-Tu MS; Section of Cell Biology and Functional Genomics, Department of Medicine, Imperial College London, Hammersmith Hospital, du Cane Road, London W12 0NN, UK.
  • Chabosseau P; Section of Cell Biology and Functional Genomics, Department of Medicine, Imperial College London, Hammersmith Hospital, du Cane Road, London W12 0NN, UK.
  • Gaulton KJ; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK; Department of Pediatrics, University of California San Diego, La Jolla, CA 92093, USA.
  • van de Bunt M; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK; Oxford Centre for Diabetes, Endocrinology & Metabolism, University of Oxford, Oxford OX3 7LJ, UK.
  • Siddiq A; Department of Genomics of Common Disease, Imperial College London, London W12 0NN, UK.
  • Falchi M; Department of Genomics of Common Disease, Imperial College London, London W12 0NN, UK; Department of Twin Research and Genetic Epidemiology, Kings College London, London SE1 7EH, UK.
  • Thurner M; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK; Oxford Centre for Diabetes, Endocrinology & Metabolism, University of Oxford, Oxford OX3 7LJ, UK.
  • Canouil M; European Genomic Institute for Diabetes (EGID), 59045 Lille, France; Lille University, 59655 Villeneuve d'Ascq Cédex, France.
  • Pattou F; European Genomic Institute for Diabetes (EGID), 59045 Lille, France; Lille University, 59655 Villeneuve d'Ascq Cédex, France.
  • Leclerc I; Section of Cell Biology and Functional Genomics, Department of Medicine, Imperial College London, Hammersmith Hospital, du Cane Road, London W12 0NN, UK.
  • Pullen TJ; Section of Cell Biology and Functional Genomics, Department of Medicine, Imperial College London, Hammersmith Hospital, du Cane Road, London W12 0NN, UK.
  • Cane MC; Section of Cell Biology and Functional Genomics, Department of Medicine, Imperial College London, Hammersmith Hospital, du Cane Road, London W12 0NN, UK.
  • Prabhala P; Section of Cell Biology and Functional Genomics, Department of Medicine, Imperial College London, Hammersmith Hospital, du Cane Road, London W12 0NN, UK.
  • Greenwald W; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK; Department of Pediatrics, University of California San Diego, La Jolla, CA 92093, USA.
  • Schulte A; Sanofi-Aventis Deutschland GmbH, 65926 Frankfurt am Main, Germany.
  • Marchetti P; Department of Endocrinology and Metabolism, University of Pisa, 56126 Pisa, Italy.
  • Ibberson M; Vital-IT Group, SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.
  • MacDonald PE; Alberta Diabetes Institute Islet Core and Department of Pharmacology, University of Alberta, Edmonton, AB T6G 2E1, Canada.
  • Manning Fox JE; Alberta Diabetes Institute Islet Core and Department of Pharmacology, University of Alberta, Edmonton, AB T6G 2E1, Canada.
  • Gloyn AL; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK; Oxford Centre for Diabetes, Endocrinology & Metabolism, University of Oxford, Oxford OX3 7LJ, UK; Oxford NIHR Biomedical Research Centre, Churchill Hospital, Old Road, Headington, Oxford OX3 7LJ,
  • Froguel P; Department of Genomics of Common Disease, Imperial College London, London W12 0NN, UK; European Genomic Institute for Diabetes (EGID), 59045 Lille, France; Lille University, 59655 Villeneuve d'Ascq Cédex, France.
  • Solimena M; Paul Langerhans Institute of the Helmholtz Center Munich at the University Hospital and Faculty of Medicine, TU Dresden, 01307 Dresden, Germany; German Center for Diabetes Research (DZD e.V), 85764 Neuherberg, Germany; Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germa
  • McCarthy MI; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK; Oxford Centre for Diabetes, Endocrinology & Metabolism, University of Oxford, Oxford OX3 7LJ, UK; Oxford NIHR Biomedical Research Centre, Churchill Hospital, Old Road, Headington, Oxford OX3 7LJ,
  • Rutter GA; Section of Cell Biology and Functional Genomics, Department of Medicine, Imperial College London, Hammersmith Hospital, du Cane Road, London W12 0NN, UK. Electronic address: g.rutter@imperial.ac.uk.
Am J Hum Genet ; 100(2): 238-256, 2017 02 02.
Article em En | MEDLINE | ID: mdl-28132686
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Diabetes Mellitus Tipo 2 / Insulina Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Am J Hum Genet Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Diabetes Mellitus Tipo 2 / Insulina Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Am J Hum Genet Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos