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Influenza A Virus Virulence Depends on Two Amino Acids in the N-Terminal Domain of Its NS1 Protein To Facilitate Inhibition of the RNA-Dependent Protein Kinase PKR.
Schierhorn, Kristina L; Jolmes, Fabian; Bespalowa, Julia; Saenger, Sandra; Peteranderl, Christin; Dzieciolowski, Julia; Mielke, Maja; Budt, Matthias; Pleschka, Stephan; Herrmann, Andreas; Herold, Susanne; Wolff, Thorsten.
Afiliação
  • Schierhorn KL; Unit 17, Influenza and other Respiratory Viruses, Robert Koch Institut, Berlin, Germany.
  • Jolmes F; Department of Biology, Molecular Biophysics, IRI Life Sciences, Humboldt Universität zu Berlin, Berlin, Germany.
  • Bespalowa J; Universities Giessen & Marburg Lung Center, Department of Internal Medicine II, Section of Infectious Diseases, German Center for Lung Research, Giessen, Germany.
  • Saenger S; Unit 17, Influenza and other Respiratory Viruses, Robert Koch Institut, Berlin, Germany.
  • Peteranderl C; Universities Giessen & Marburg Lung Center, Department of Internal Medicine II, Section of Infectious Diseases, German Center for Lung Research, Giessen, Germany.
  • Dzieciolowski J; Institute of Medical Virology, Justus Liebig University Giessen, Giessen, Germany.
  • Mielke M; Department of Biology, Molecular Biophysics, IRI Life Sciences, Humboldt Universität zu Berlin, Berlin, Germany.
  • Budt M; Unit 17, Influenza and other Respiratory Viruses, Robert Koch Institut, Berlin, Germany.
  • Pleschka S; Institute of Medical Virology, Justus Liebig University Giessen, Giessen, Germany.
  • Herrmann A; Department of Biology, Molecular Biophysics, IRI Life Sciences, Humboldt Universität zu Berlin, Berlin, Germany.
  • Herold S; Universities Giessen & Marburg Lung Center, Department of Internal Medicine II, Section of Infectious Diseases, German Center for Lung Research, Giessen, Germany.
  • Wolff T; Unit 17, Influenza and other Respiratory Viruses, Robert Koch Institut, Berlin, Germany wolfft@rki.de.
J Virol ; 91(10)2017 05 15.
Article em En | MEDLINE | ID: mdl-28250123
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus da Influenza A / Proteínas não Estruturais Virais / EIF-2 Quinase / Aminoácidos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Virol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Estados Unidos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus da Influenza A / Proteínas não Estruturais Virais / EIF-2 Quinase / Aminoácidos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Virol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Estados Unidos