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Neuropathic pain and quality of life after wide local excision and sentinel lymph node biopsy for melanoma: a multicentre study.
Thomson, Collette H; Cassell, Oliver; Peach, Howard; Holloway, Samantha; Garioch, Jennifer; Moncrieff, Marc.
Afiliação
  • Thomson CH; aDepartment of Plastic Surgery, Norfolk and Norwich University Hospital, NorwichbDepartment of Plastic Surgery, Oxford University Hospitals NHS Foundation Trust, OxfordcDepartment of Plastic Surgery, Leeds Teaching Hospitals NHS Trust, LeedsdSchool of Medicine, Centre for Medical Education, Cardiff University, Cardiff, UK.
Melanoma Res ; 27(2): 121-125, 2017 04.
Article em En | MEDLINE | ID: mdl-28253208
ABSTRACT
Wide local excision and sentinel lymph node biopsy is the mainstay of treatment for patients with melanoma. As survival outcomes improve, longer term quality of life questions become more pertinent and this study aims to assess the factors which may play a role following surgery. A total of, 221 patients who underwent wide local excision and sentinel lymph node biopsy for melanoma (AJCC stage I and II) were recruited from three UK centres. These patients completed a patient outcome questionnaire, which included demographic and treatment data as well as quality of life and pain questionnaires. Pain was the only significant factor influencing the quality of life with a negative correlation seen between pain and quality of life scores (P<0.001). In total, 34% of patients reported pain at their surgical site and four (1.8%) patients scored as high risk for neuropathic pain. Patients experiencing pain were significantly younger that those not reporting pain (median 55.0 vs. 63.5 years, P<0.001). Length of time since surgery did not correlate with pain nor quality of life scores. Our results suggest that following this common procedure a sizeable proportion of patients experience pain and poorer quality of life which does not improve with time. The level of pain experienced is clinically significant and merits evaluation and treatment in this group of patients who are increasingly surviving their melanoma diagnosis. Further investigation into potential prophylactic measures is suggested.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Complicações Pós-Operatórias / Qualidade de Vida / Neoplasias Cutâneas / Melanoma / Neuralgia Tipo de estudo: Clinical_trials Aspecto: Patient_preference Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Melanoma Res Assunto da revista: NEOPLASIAS Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Complicações Pós-Operatórias / Qualidade de Vida / Neoplasias Cutâneas / Melanoma / Neuralgia Tipo de estudo: Clinical_trials Aspecto: Patient_preference Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Melanoma Res Assunto da revista: NEOPLASIAS Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido