Differences in bone mineral density between normal-weight children and children with overweight and obesity: a systematic review and meta-analysis.
Obes Rev
; 18(5): 526-546, 2017 05.
Article
em En
| MEDLINE
| ID: mdl-28273691
ABSTRACT
OBJECTIVE:
This study examines the differences in bone mineral density between normal-weight children and children with overweight or obesity.METHODS:
A systematic review and meta-analysis of observational studies (published up to 22 June 2016) on the differences in bone mineral density between normal-weight children and overweight and obese children was performed. Results were pooled when possible and mean differences (MDs) were calculated between normal-weight and overweight and normal-weight and obese children for bone content and density measures at different body sites.RESULTS:
Twenty-seven studies, with a total of 5,958 children, were included. There was moderate and high quality of evidence that overweight (MD 213 g; 95% confidence interval [CI] 166, 261) and obese children (MD 329 g; 95%CI [229, 430]) have a significantly higher whole body bone mineral content than normal-weight children. Similar results were found for whole body bone mineral density. Sensitivity analysis showed that the association was stronger in girls.CONCLUSIONS:
Overweight and obese children have a significantly higher bone mineral density compared with normal-weight children. Because there was only one study included with a longitudinal design, the long-term impact of childhood overweight and obesity on bone health at adulthood is not clear.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Densidade Óssea
/
Sobrepeso
/
Obesidade Infantil
Tipo de estudo:
Diagnostic_studies
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Observational_studies
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Systematic_reviews
Limite:
Child
/
Humans
Idioma:
En
Revista:
Obes Rev
Assunto da revista:
METABOLISMO
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Holanda