Optical coherence tomography angiography of the peripapillary retina and optic nerve head in dominant optic atrophy.
Mitochondrion
; 36: 60-65, 2017 09.
Article
em En
| MEDLINE
| ID: mdl-28286264
ABSTRACT
Peripapillar and nerve head vessel density (VD) was measured in 10 patients affected by Dominant optic atrophy (DOA) using optical coherence tomography angiography (OCT-A) and compared to the measurements of 15 age- and gender-matched controls. DOA patients showed VD reduction, mostly in the temporal and inferotemporal peripapillary sectors, according to the preferential involvement of the papillomacular bundle. Despite poor best-corrected visual acuity (BCVA), OCT-A revealed good repeatability. VD correlated with functional (mean deviation of visual field and BCVA) and structural (retinal nerve fiber layer thickness) parameters and could be a non-invasive, quantitative tool for the monitoring of the disease and of the therapeutic approaches.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Disco Óptico
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Atrofia
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Vasos Sanguíneos
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Angiografia
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Atrofia Óptica Autossômica Dominante
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Tomografia de Coerência Óptica
Tipo de estudo:
Evaluation_studies
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Observational_studies
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Prevalence_studies
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Risk_factors_studies
Limite:
Adolescent
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Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Mitochondrion
Ano de publicação:
2017
Tipo de documento:
Article