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HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures.
Davies, Helen; Glodzik, Dominik; Morganella, Sandro; Yates, Lucy R; Staaf, Johan; Zou, Xueqing; Ramakrishna, Manasa; Martin, Sancha; Boyault, Sandrine; Sieuwerts, Anieta M; Simpson, Peter T; King, Tari A; Raine, Keiran; Eyfjord, Jorunn E; Kong, Gu; Borg, Åke; Birney, Ewan; Stunnenberg, Hendrik G; van de Vijver, Marc J; Børresen-Dale, Anne-Lise; Martens, John W M; Span, Paul N; Lakhani, Sunil R; Vincent-Salomon, Anne; Sotiriou, Christos; Tutt, Andrew; Thompson, Alastair M; Van Laere, Steven; Richardson, Andrea L; Viari, Alain; Campbell, Peter J; Stratton, Michael R; Nik-Zainal, Serena.
Afiliação
  • Davies H; Wellcome Trust Sanger Institute, Hinxton, UK.
  • Glodzik D; Wellcome Trust Sanger Institute, Hinxton, UK.
  • Morganella S; Wellcome Trust Sanger Institute, Hinxton, UK.
  • Yates LR; Wellcome Trust Sanger Institute, Hinxton, UK.
  • Staaf J; Guy's and St Thomas' NHS Trust, London, UK.
  • Zou X; Division of Oncology and Pathology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
  • Ramakrishna M; Wellcome Trust Sanger Institute, Hinxton, UK.
  • Martin S; Wellcome Trust Sanger Institute, Hinxton, UK.
  • Boyault S; Oncology, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Little Chesterford, UK.
  • Sieuwerts AM; Wellcome Trust Sanger Institute, Hinxton, UK.
  • Simpson PT; Translational Research Lab Department, Centre Léon Bérard, Lyon, France.
  • King TA; Department of Medical Oncology, Erasmus MC Cancer Institute and Cancer Genomics, Erasmus University Medical Center, Rotterdam, the Netherlands.
  • Raine K; Centre for Clinical Research and School of Medicine, The University of Queensland, Brisbane, Queensland, Australia.
  • Eyfjord JE; Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Kong G; Wellcome Trust Sanger Institute, Hinxton, UK.
  • Borg Å; Cancer Research Laboratory, Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
  • Birney E; Department of Pathology, College of Medicine, Hanyang University, Seoul, Republic of Korea.
  • Stunnenberg HG; Division of Oncology and Pathology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
  • van de Vijver MJ; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, UK.
  • Børresen-Dale AL; Department of Molecular Biology, Faculties of Science and Medicine, Radboud University, Nijmegen, the Netherlands.
  • Martens JW; Department of Pathology, Academic Medical Center, Amsterdam, the Netherlands.
  • Span PN; Department of Cancer Genetics, Institute for Cancer Research, Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.
  • Lakhani SR; K.G. Jebsen Centre for Breast Cancer Research, Institute for Clinical Medicine, University of Oslo, Oslo, Norway.
  • Vincent-Salomon A; Department of Medical Oncology, Erasmus MC Cancer Institute and Cancer Genomics, Erasmus University Medical Center, Rotterdam, the Netherlands.
  • Sotiriou C; Department of Radiation Oncology, Radboud University Medical Center, Nijmegen, the Netherlands.
  • Tutt A; Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.
  • Thompson AM; Centre for Clinical Research and School of Medicine, The University of Queensland, Brisbane, Queensland, Australia.
  • Van Laere S; Pathology Queensland, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia.
  • Richardson AL; Department of Pathology, Institut Curie, Paris, France.
  • Viari A; INSERM U934, Institut Curie, Paris, France.
  • Campbell PJ; Breast Cancer Translational Research Laboratory, Université Libre de Bruxelles, Institut Jules Bordet, Brussels, Belgium.
  • Stratton MR; Breast Cancer Now Research Unit, King's College, London, UK.
  • Nik-Zainal S; Breast Cancer Now Toby Robin's Research Centre, Institute of Cancer Research, London, UK.
Nat Med ; 23(4): 517-525, 2017 Apr.
Article em En | MEDLINE | ID: mdl-28288110
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Neoplasias Pancreáticas / Neoplasias da Mama / Proteína BRCA1 / Proteína BRCA2 / Mutação Tipo de estudo: Prognostic_studies Limite: Female / Humans / Male Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Neoplasias Pancreáticas / Neoplasias da Mama / Proteína BRCA1 / Proteína BRCA2 / Mutação Tipo de estudo: Prognostic_studies Limite: Female / Humans / Male Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos