Five new koumine-type alkaloids from the roots of Gelsemium elegans.
Fitoterapia
; 118: 112-117, 2017 Apr.
Article
em En
| MEDLINE
| ID: mdl-28300700
ABSTRACT
Five new koumine-type alkaloids (1-5) along with six known ones were isolated from the roots of Gelsemium elegans. Their structures with absolute configurations were elucidated on the basis of NMR spectroscopy and electronic circular dichroism spectral analyses. The inhibitory effects of compounds 1-11 on the viability of three tumor cell lines (A-649, HepG2, and HuH7) were evaluated by the MTT assay.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Alcaloides Indólicos
/
Gelsemium
Limite:
Humans
Idioma:
En
Revista:
Fitoterapia
Ano de publicação:
2017
Tipo de documento:
Article