Hemophagocytic syndrome secondary to tuberculosis at 24-week gestation.
Int J Mycobacteriol
; 6(1): 108-110, 2017.
Article
em En
| MEDLINE
| ID: mdl-28317816
ABSTRACT
Hemophagocytic syndrome is a life-threatening disease characterized by the uncontrolled activation of macrophages, resulting in hemophagocytosis of blood cells in the bone marrow. A 20-year-old gravida at 23-week and 5-day gestation was admitted to hospital to evaluate fever up to 104°F of unknown origin, moderate cytopenia, and elevated levels of liver enzymes. Bone marrow biopsy confirmed hemophagocytic syndrome, and polymerase chain reaction came back positive for Mycobacterium tuberculosis. Supportive care and tuberculosis treatment resulted in clinical improvement. At 27 weeks and 5 days, premature rupture of the membranes occurred, and because of the high probability of reactivating the hemophagocytic syndrome, a cesarean section was performed at 29-week and 2-day gestation. Hemophagocytic syndrome is an uncommon disease which rarely appears during pregnancy. Early diagnosis and treatment can save both maternal and fetal lives.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Complicações Infecciosas na Gravidez
/
Tuberculose
/
Linfo-Histiocitose Hemofagocítica
/
Mycobacterium tuberculosis
Tipo de estudo:
Screening_studies
Limite:
Adult
/
Female
/
Humans
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Newborn
/
Pregnancy
Idioma:
En
Revista:
Int J Mycobacteriol
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Espanha