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Diversity and bioactive potentials of culturable heterotrophic bacteria from the surficial sediments of the Arabian Sea.
Anas, Abdulaziz; Nilayangod, Charulatha; Jasmin, C; Vinothkumar, Saradavey; Parameswaran, P S; Nair, Shanta.
Afiliação
  • Anas A; CSIR-National Institute of Oceanography, Regional Centre, Kochi, Kerala, 682 018, India. anas@nio.org.
  • Nilayangod C; CSIR-National Institute of Oceanography, Regional Centre, Kochi, Kerala, 682 018, India.
  • Jasmin C; CSIR-National Institute of Oceanography, Regional Centre, Kochi, Kerala, 682 018, India.
  • Vinothkumar S; CSIR-National Institute of Oceanography, Regional Centre, Kochi, Kerala, 682 018, India.
  • Parameswaran PS; CSIR-National Institute of Oceanography, Regional Centre, Kochi, Kerala, 682 018, India.
  • Nair S; CSIR-National Institute of Oceanography, Regional Centre, Kochi, Kerala, 682 018, India.
3 Biotech ; 6(2): 238, 2016 Dec.
Article em En | MEDLINE | ID: mdl-28330310
Marine sediments accommodate plethora of diverse microorganisms with varying ecological functions. In the present study, we isolated bacteria from surficial sediments of south east Arabian Sea (AS) and evaluated their bioactive potentials. A total of 131 isolates belonging to the phylum: γ-Proteobacteria (63%), Bacillales (34%) and Micrococcaceae (3%) were isolated. Among these, about 40% of the isolates showed the presence of secondary metabolite biosynthetic genes such as PKS or NRPS or both. Organic extracts of nearly 50% of these organisms were cytotoxic to human breast cancer MCF-7 cells and were bactericidal to human pathogens, Escherichia coli and Pseudomonas sp., while 20-30% of them were bactericidal to Vibrio sp. and Staphylococcus sp. too. In all, 8 isolates, belonging to Pseudomonas spp., Bacillus sp. and/or Lysinibacillus sp. displayed high level of bactericidal/cytotoxic properties. The study proposes AS sediment as a rich source for microorganisms with prospective bioactive molecules.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: 3 Biotech Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Índia País de publicação: Alemanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: 3 Biotech Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Índia País de publicação: Alemanha