Future Prospects of Biologic Therapies for Immunologic Diseases.

Kumar, Santhosh; Ward, Brant R; Irani, Anne-Marie

Kumar, Santhosh; Ward, Brant R; Irani, Anne-Marie.

Afiliação

Kumar S; Division of Allergy and Immunology, Children's Hospital of Richmond, Virginia Commonwealth University, CHoR Pavilion, 5th Floor, 1000 East Broad Street, Richmond, VA 23298-0225, USA. Electronic address: santhosh.kumar@vcuhealth.org.
Ward BR; Division of Allergy and Immunology, Children's Hospital of Richmond, Virginia Commonwealth University, CHoR Pavilion, 5th Floor, 1000 East Broad Street, Richmond, VA 23298-0225, USA; Division of Rheumatology, Allergy, and Immunology, Virginia Commonwealth University, McGuire Hall, Room 4-115A, 1112 East Clay Street, Richmond, VA 23298-0263, USA; Department of Microbiology and Immunology, Virginia Commonwealth University, 1101 East Marshall Street, P.O. Box 980678, Richmond, VA 23298, USA.
Irani AM; Division of Allergy and Immunology, Children's Hospital of Richmond, Virginia Commonwealth University, CHoR Pavilion, 5th Floor, 1000 East Broad Street, Richmond, VA 23298-0225, USA.

Immunol Allergy Clin North Am ; 37(2): 431-448, 2017 05.

Article em En | MEDLINE | ID: mdl-28366486

ABSTRACT

ABSTRACT

This article presents an overview of future uses for biologic therapies in the treatment of immunologic and allergic conditions. Discussion is centered on the use of existing therapies outside of their current indication or on new therapies that are close to approval. This information may help familiarize practicing allergists and immunologists with therapies they may soon encounter in their practice as well as help identify conditions and treatments that will require further study in the near future.

Assuntos

Terapia Biológica; Doenças do Sistema Imunitário/terapia; Anticorpos Anti-Idiotípicos/farmacologia; Anticorpos Anti-Idiotípicos/uso terapêutico; Anticorpos Monoclonais/farmacologia; Anticorpos Monoclonais/uso terapêutico; Produtos Biológicos/farmacologia; Produtos Biológicos/uso terapêutico; Terapia Biológica/métodos; Terapia Biológica/tendências; Citocinas/antagonistas & inibidores; Citocinas/metabolismo; Dessensibilização Imunológica; Gerenciamento Clínico; Humanos; Doenças do Sistema Imunitário/diagnóstico; Doenças do Sistema Imunitário/imunologia; Doenças do Sistema Imunitário/metabolismo; Terapia de Alvo Molecular; Receptores de Citocinas/antagonistas & inibidores; Receptores de Citocinas/metabolismo; Transdução de Sinais/efeitos dos fármacos

Palavras-chave

Asthma; Atopic dermatitis; Biologic; Churg-Strauss syndrome; Hemophagocytic lymphohistiocytosis; Immune dysregulation; Immunodeficiency; Mastocytosis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Terapia Biológica / Doenças do Sistema Imunitário Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans Idioma: En Revista: Immunol Allergy Clin North Am Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2017 Tipo de documento: Article

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