ESCRTing Necroptosis.

Guo, Hongyan; Kaiser, William J

Guo, Hongyan; Kaiser, William J.

Afiliação

Guo H; Department of Microbiology, Immunology, and Molecular Genetics, University of Texas Heath San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.
Kaiser WJ; Department of Microbiology, Immunology, and Molecular Genetics, University of Texas Heath San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA. Electronic address: kaiserw@uthscsa.edu.

Cell ; 169(2): 186-187, 2017 04 06.

Article em En | MEDLINE | ID: mdl-28388403

ABSTRACT

ABSTRACT

Necroptosis is a highly inflammatory form of programmed cell death that results from MLKL-mediated disruption of the cell membrane. In this issue of Cell, Gong et al. challenge the notion that MLKL activation is a point of no return by identifying mechanisms to counterbalance necroptosis, sustain plasma membrane integrity, and prolong cell viability.

Assuntos

Proteínas Quinases; Proteína Serina-Treonina Quinases de Interação com Receptores; Apoptose; Necrose; Fosforilação

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Quinases / Proteína Serina-Treonina Quinases de Interação com Receptores Idioma: En Revista: Cell Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos

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