Persistence of a t(11;14)-positive clone in a patient with mantle cell lymphoma for 20 years.

Otsuka, Yasuyuki; Nishikori, Momoko; Kitano, Toshiyuki; Oka, Tomomi; Ishikawa, Takayuki; Haga, Hironori; Takaori-Kondo, Akifumi

Persistence of a t(11;14)-positive clone in a patient with mantle cell lymphoma for 20 years.

Otsuka, Yasuyuki; Nishikori, Momoko; Kitano, Toshiyuki; Oka, Tomomi; Ishikawa, Takayuki; Haga, Hironori; Takaori-Kondo, Akifumi.

Afiliação

Otsuka Y; Department of Hematology and Oncology Graduate School of Medicine Kyoto University Kyoto Japan.
Nishikori M; Department of Hematology and Oncology Graduate School of Medicine Kyoto University Kyoto Japan.
Kitano T; Department of Hematology and Oncology Graduate School of Medicine Kyoto University Kyoto Japan.
Oka T; Department of Hematology and Oncology Graduate School of Medicine Kyoto University Kyoto Japan.
Ishikawa T; Department of Hematology Kobe City Medical Center General Hospital Kobe Japan.
Haga H; Department of Pathology Kyoto University Hospital Kyoto Japan.
Takaori-Kondo A; Department of Hematology and Oncology Graduate School of Medicine Kyoto University Kyoto Japan.

Clin Case Rep ; 5(4): 477-481, 2017 Apr.

Article em En | MEDLINE | ID: mdl-28396772

ABSTRACT

ABSTRACT

We report here a patient with extremely indolent mantle cell lymphoma (MCL) who had progressed and required immunochemotherapy 20 years after diagnostic splenectomy. Non-nodal, indolent MCL patients may progress after such an extraordinary long indolent phase, and we recommend lifelong follow up for such cases.

Palavras-chave

Cyclin D1; Sox11; Splenectomy; mantle cell lymphoma; somatic hypermutation analysis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Clin Case Rep Ano de publicação: 2017 Tipo de documento: Article