Epilepsy surgery for epileptic encephalopathy as a sequela of herpes simplex encephalitis: case report.
J Neurosurg Pediatr
; 20(1): 56-63, 2017 Jul.
Article
em En
| MEDLINE
| ID: mdl-28452654
ABSTRACT
Herpes simplex virus (HSV) encephalitis can manifest with different clinical presentations, including acute monophasic illness and biphasic chronic granulomatous HSV encephalitis. Chronic encephalitis is much less common, and very rare late relapses are associated with intractable epilepsy and progressive neurological deficits with or without evidence of HSV in the cerebrospinal fluid. The authors report on an 8-year-old girl with a history of treated HSV-1 encephalitis when she was 13 months of age and focal epilepsy when she was 2 years old. Although free of clinical seizures, when she was 5, she experienced behavioral and academic dysfunction, which was later attributed to electrographic focal seizures and worsening electroencephalography (EEG) findings with electrical status epilepticus during slow-wave sleep (ESES). Following a right temporal lobectomy, chronic granulomatous encephalitis was diagnosed. The patient's clinical course improved with the resolution of seizures and EEG abnormalities.
Palavras-chave
BBB = blood-brain barrier; CNS = central nervous system; CSF = cerebrospinal fluid; ECoG = electrocorticography; EEG = electroencephalography; ESES; ESES = electrical status epilepticus in slow-wave sleep; HSV = herpes simplex virus; NREM = nonrapid eye movement; PCR = polymerase chain reaction; TLR = Toll-like receptor; epilepsy surgery; epileptic encephalopathy; herpes simplex virus encephalitis
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Herpesvirus Humano 1
/
Encefalite por Herpes Simples
/
Epilepsia Resistente a Medicamentos
Limite:
Child
/
Female
/
Humans
Idioma:
En
Revista:
J Neurosurg Pediatr
Assunto da revista:
NEUROCIRURGIA
/
PEDIATRIA
Ano de publicação:
2017
Tipo de documento:
Article