Deciphering Pancreatic Islet ß Cell and &#945; Cell Maturation Pathways and Characteristic Features at the Single-Cell Level.

Qiu, Wei-Lin; Zhang, Yu-Wei; Feng, Ye; Li, Lin-Chen; Yang, Liu; Xu, Cheng-Ran

Deciphering Pancreatic Islet ß Cell and α Cell Maturation Pathways and Characteristic Features at the Single-Cell Level.

Qiu, Wei-Lin; Zhang, Yu-Wei; Feng, Ye; Li, Lin-Chen; Yang, Liu; Xu, Cheng-Ran.

Afiliação

Qiu WL; Ministry of Education Key Laboratory of Cell Proliferation, College of Life Sciences, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China; PKU-Tsinghua-NIBS Graduate Program, Peking University, Beijing 100871, China.
Zhang YW; Ministry of Education Key Laboratory of Cell Proliferation, College of Life Sciences, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China.
Feng Y; Ministry of Education Key Laboratory of Cell Proliferation, College of Life Sciences, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China; PKU-Tsinghua-NIBS Graduate Program, Peking University, Beijing 100871, China.
Li LC; Ministry of Education Key Laboratory of Cell Proliferation, College of Life Sciences, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China.
Yang L; Ministry of Education Key Laboratory of Cell Proliferation, College of Life Sciences, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China; Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China.
Xu CR; Ministry of Education Key Laboratory of Cell Proliferation, College of Life Sciences, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China. Electronic address: cxu@pku.edu.cn.

Cell Metab ; 25(5): 1194-1205.e4, 2017 May 02.

Article em En | MEDLINE | ID: mdl-28467935

Assuntos

Células Secretoras de Glucagon/citologia; Células Secretoras de Insulina/citologia; Animais; Ciclo Celular; Diferenciação Celular; Proliferação de Células; Células Cultivadas; Feminino; Células Secretoras de Glucagon/metabolismo; Células Secretoras de Insulina/metabolismo; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Transdução de Sinais; Análise de Célula Única; Transcriptoma

Palavras-chave

maturation; neogenesis; pancreatic islet; proliferation; single-cell RNA-seq; α cell; ß cell; ß cell heterogeneity

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Secretoras de Glucagon / Células Secretoras de Insulina Limite: Animals Idioma: En Revista: Cell Metab Assunto da revista: METABOLISMO Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos

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