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Maternal immune activation results in complex microglial transcriptome signature in the adult offspring that is reversed by minocycline treatment.
Mattei, D; Ivanov, A; Ferrai, C; Jordan, P; Guneykaya, D; Buonfiglioli, A; Schaafsma, W; Przanowski, P; Deuther-Conrad, W; Brust, P; Hesse, S; Patt, M; Sabri, O; Ross, T L; Eggen, B J L; Boddeke, E W G M; Kaminska, B; Beule, D; Pombo, A; Kettenmann, H; Wolf, S A.
Afiliação
  • Mattei D; Cellular Neurocience, Max-Delbrueck-Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
  • Ivanov A; Core Unit Bioinformatics, Berlin Institute of Health, Berlin, Germany.
  • Ferrai C; Charite Medical University, Berlin, Germany.
  • Jordan P; Epigenetic Regulation and Chromatin Architecture Group, Berlin Institute for Medical Systems Biology, Max-Delbrück Centre for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
  • Guneykaya D; Cellular Neurocience, Max-Delbrueck-Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
  • Buonfiglioli A; Cellular Neurocience, Max-Delbrueck-Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
  • Schaafsma W; Cellular Neurocience, Max-Delbrueck-Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
  • Przanowski P; Institute of Cell Biology and Neurobiology, Charité-Universitaetsmedizin, Berlin, Germany.
  • Deuther-Conrad W; Department of Neuroscience, Section Medical Physiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
  • Brust P; Laboratory of Molecular Neurobiology, Nencki Institute of Experimental Biology, Warsaw, Poland.
  • Hesse S; Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Research Site Leipzig, Helmholtz-Zentrum Dresden-Rossendorf, Leipzig, Germany.
  • Patt M; Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Research Site Leipzig, Helmholtz-Zentrum Dresden-Rossendorf, Leipzig, Germany.
  • Sabri O; Department of Nuclear Medicine, University of Leipzig, Leipzig, Germany.
  • Ross TL; Integrated Treatment and Research Centre (IFB) Adiposity Diseases, University of Leipzig, Leipzig, Germany.
  • Eggen BJL; Department of Nuclear Medicine, University of Leipzig, Leipzig, Germany.
  • Boddeke EWGM; Department of Nuclear Medicine, University of Leipzig, Leipzig, Germany.
  • Kaminska B; Department of Nuclear Medicine, Hannover Medical School, Hannover, Germany.
  • Beule D; Department of Neuroscience, Section Medical Physiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
  • Pombo A; Department of Neuroscience, Section Medical Physiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
  • Kettenmann H; Laboratory of Molecular Neurobiology, Nencki Institute of Experimental Biology, Warsaw, Poland.
  • Wolf SA; Core Unit Bioinformatics, Berlin Institute of Health, Berlin, Germany.
Transl Psychiatry ; 7(5): e1120, 2017 05 09.
Article em En | MEDLINE | ID: mdl-28485733
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Microglia / Transmissão Sináptica / Filhos Adultos / Fenômenos do Sistema Imunitário / Transcriptoma / Minociclina / Antibacterianos Limite: Animals / Female / Humans / Pregnancy Idioma: En Revista: Transl Psychiatry Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Microglia / Transmissão Sináptica / Filhos Adultos / Fenômenos do Sistema Imunitário / Transcriptoma / Minociclina / Antibacterianos Limite: Animals / Female / Humans / Pregnancy Idioma: En Revista: Transl Psychiatry Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Estados Unidos