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W2476 ameliorates ß-cell dysfunction and exerts therapeutic effects in mouse models of diabetes via modulation of the thioredoxin-interacting protein signaling pathway.
Li, Ting; Lin, Guang-Yao; Zhong, Li; Zhou, Yan; Wang, Jia; Zhu, Yue; Feng, Yang; Cai, Xiao-Qing; Liu, Qing; Nosjean, Olivier; Boutin, Jean A; Renard, Pierre; Yang, De-Hua; Wang, Ming-Wei.
Afiliação
  • Li T; The National Center for Drug Screening and the CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Lin GY; University of Chinese Academy of Sciences, Beijing 100049, China.
  • Zhong L; University of Chinese Academy of Sciences, Beijing 100049, China.
  • Zhou Y; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
  • Wang J; The National Center for Drug Screening and the CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Zhu Y; University of Chinese Academy of Sciences, Beijing 100049, China.
  • Feng Y; The National Center for Drug Screening and the CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Cai XQ; The National Center for Drug Screening and the CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Liu Q; The National Center for Drug Screening and the CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Nosjean O; University of Chinese Academy of Sciences, Beijing 100049, China.
  • Boutin JA; The National Center for Drug Screening and the CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Renard P; The National Center for Drug Screening and the CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Yang DH; The National Center for Drug Screening and the CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Wang MW; Pôle d'Expertise Biotechnologie, Chimie et Biologie, Institut de Recherches SERVIER, Croissy-sur-Seine 78290, France.
Acta Pharmacol Sin ; 38(7): 1024-1037, 2017 Jul.
Article em En | MEDLINE | ID: mdl-28502980
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tiorredoxinas / Adenina / Transdução de Sinais / Proteínas de Transporte / Diabetes Mellitus Experimental / Modelos Animais de Doenças / Células Secretoras de Insulina Limite: Animals Idioma: En Revista: Acta Pharmacol Sin Assunto da revista: FARMACOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tiorredoxinas / Adenina / Transdução de Sinais / Proteínas de Transporte / Diabetes Mellitus Experimental / Modelos Animais de Doenças / Células Secretoras de Insulina Limite: Animals Idioma: En Revista: Acta Pharmacol Sin Assunto da revista: FARMACOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos