The Identity of "Chromium Malate".
Biol Trace Elem Res
; 181(2): 369-377, 2018 Feb.
Article
em En
| MEDLINE
| ID: mdl-28516390
ABSTRACT
Recently, several studies on the effects of a compound named "chromium malate," with the proposed formula "Cr2malate3·xH2O" where x = 3.5 or 5, on the health of healthy and diabetic rats have appeared. However, the compound is poorly characterized, and knowing the identity of this material could be important in the interpretation of the previous and of future studies on the effects of this compound in animals. Consequently, the synthesis, characterization, and identity of this material were explored. A combination of spectroscopic, magnetic, and elemental analyses and mass spectral studies reveal that the compound is probably a polymer, not a discrete molecule, and does not have the composition previously reported. The repeating unit of the polymer possesses an antiferromagnetically coupled trinuclear Cr(III) core. The current study suggests that previous reports on chromium malate and its effects in animals must be viewed with caution.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Compostos de Cromo
/
Malatos
Idioma:
En
Revista:
Biol Trace Elem Res
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Estados Unidos