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Iontophoretic administration of pirprofen or lysine soluble aspirin in the treatment of rheumatic diseases.
Garagiola, U; Dacatra, U; Braconaro, F; Porretti, E; Pisetti, A; Azzolini, V.
Afiliação
  • Garagiola U; Ciba-Geigy S.p.A., Medical Department, Origgio (VA), Italy.
Clin Ther ; 10(5): 553-8, 1988.
Article em En | MEDLINE | ID: mdl-2856598
ABSTRACT
A double-blind study was designed to compare the efficacy and tolerability of pirprofen and lysine soluble aspirin administered by iontophoresis to 80 patients with various painful rheumatic diseases. Treatment lasted two weeks, with five administrations a week, each lasting 20 minutes (direct current; mean intensity, 2.3 mA). After five administrations, patients showed significant improvement in pain at rest and on movement, with no significant differences between pirprofen and aspirin. Final results were excellent or good in about 75% of the patients treated and functional improvement was satisfactory in about 80%. There were no side effects.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dor / Fenilpropionatos / Anti-Inflamatórios não Esteroides / Aspirina / Doenças Reumáticas / Lisina Tipo de estudo: Clinical_trials / Etiology_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Ther Ano de publicação: 1988 Tipo de documento: Article País de afiliação: Itália
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dor / Fenilpropionatos / Anti-Inflamatórios não Esteroides / Aspirina / Doenças Reumáticas / Lisina Tipo de estudo: Clinical_trials / Etiology_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Ther Ano de publicação: 1988 Tipo de documento: Article País de afiliação: Itália