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Chirality Dependent Potency Enhancement and Structural Impact of Glycol Nucleic Acid Modification on siRNA.
Schlegel, Mark K; Foster, Donald J; Kel'in, Alexander V; Zlatev, Ivan; Bisbe, Anna; Jayaraman, Muthusamy; Lackey, Jeremy G; Rajeev, Kallanthottathil G; Charissé, Klaus; Harp, Joel; Pallan, Pradeep S; Maier, Martin A; Egli, Martin; Manoharan, Muthiah.
Afiliação
  • Schlegel MK; Alnylam Pharmaceuticals , 300 Third Street, Cambridge, Massachusetts 02142, United States.
  • Foster DJ; Alnylam Pharmaceuticals , 300 Third Street, Cambridge, Massachusetts 02142, United States.
  • Kel'in AV; Alnylam Pharmaceuticals , 300 Third Street, Cambridge, Massachusetts 02142, United States.
  • Zlatev I; Alnylam Pharmaceuticals , 300 Third Street, Cambridge, Massachusetts 02142, United States.
  • Bisbe A; Alnylam Pharmaceuticals , 300 Third Street, Cambridge, Massachusetts 02142, United States.
  • Jayaraman M; Alnylam Pharmaceuticals , 300 Third Street, Cambridge, Massachusetts 02142, United States.
  • Lackey JG; Alnylam Pharmaceuticals , 300 Third Street, Cambridge, Massachusetts 02142, United States.
  • Rajeev KG; Alnylam Pharmaceuticals , 300 Third Street, Cambridge, Massachusetts 02142, United States.
  • Charissé K; Alnylam Pharmaceuticals , 300 Third Street, Cambridge, Massachusetts 02142, United States.
  • Harp J; Vanderbilt University School of Medicine , Department of Biochemistry, Nashville, Tennessee 37232, United States.
  • Pallan PS; Vanderbilt University School of Medicine , Department of Biochemistry, Nashville, Tennessee 37232, United States.
  • Maier MA; Alnylam Pharmaceuticals , 300 Third Street, Cambridge, Massachusetts 02142, United States.
  • Egli M; Vanderbilt University School of Medicine , Department of Biochemistry, Nashville, Tennessee 37232, United States.
  • Manoharan M; Alnylam Pharmaceuticals , 300 Third Street, Cambridge, Massachusetts 02142, United States.
J Am Chem Soc ; 139(25): 8537-8546, 2017 06 28.
Article em En | MEDLINE | ID: mdl-28570818
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácidos Nucleicos / RNA Interferente Pequeno / Glicóis Limite: Animals Idioma: En Revista: J Am Chem Soc Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácidos Nucleicos / RNA Interferente Pequeno / Glicóis Limite: Animals Idioma: En Revista: J Am Chem Soc Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos