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Transcriptional activation of RagD GTPase controls mTORC1 and promotes cancer growth.
Di Malta, Chiara; Siciliano, Diletta; Calcagni, Alessia; Monfregola, Jlenia; Punzi, Simona; Pastore, Nunzia; Eastes, Andrea N; Davis, Oliver; De Cegli, Rossella; Zampelli, Angela; Di Giovannantonio, Luca G; Nusco, Edoardo; Platt, Nick; Guida, Alessandro; Ogmundsdottir, Margret Helga; Lanfrancone, Luisa; Perera, Rushika M; Zoncu, Roberto; Pelicci, Pier Giuseppe; Settembre, Carmine; Ballabio, Andrea.
Afiliação
  • Di Malta C; Telethon Institute of Genetics and Medicine (TIGEM), Via Campi Flegrei 34, 80078 Pozzuoli, Naples, Italy.
  • Siciliano D; Telethon Institute of Genetics and Medicine (TIGEM), Via Campi Flegrei 34, 80078 Pozzuoli, Naples, Italy.
  • Calcagni A; Telethon Institute of Genetics and Medicine (TIGEM), Via Campi Flegrei 34, 80078 Pozzuoli, Naples, Italy.
  • Monfregola J; Telethon Institute of Genetics and Medicine (TIGEM), Via Campi Flegrei 34, 80078 Pozzuoli, Naples, Italy.
  • Punzi S; Department of Experimental Oncology, European Institute of Oncology, 20139 Milan, Italy.
  • Pastore N; Department of Molecular and Human Genetics and Neurological Research Institute, Baylor College of Medicine, Houston, TX 77030, USA.
  • Eastes AN; Department of Anatomy and Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA 94143, USA.
  • Davis O; Department of Molecular and Cellular Biology and Paul F. Glenn Center for Aging Research, University of California, Berkeley, Berkeley, CA 94720, USA.
  • De Cegli R; Telethon Institute of Genetics and Medicine (TIGEM), Via Campi Flegrei 34, 80078 Pozzuoli, Naples, Italy.
  • Zampelli A; Telethon Institute of Genetics and Medicine (TIGEM), Via Campi Flegrei 34, 80078 Pozzuoli, Naples, Italy.
  • Di Giovannantonio LG; Telethon Institute of Genetics and Medicine (TIGEM), Via Campi Flegrei 34, 80078 Pozzuoli, Naples, Italy.
  • Nusco E; Telethon Institute of Genetics and Medicine (TIGEM), Via Campi Flegrei 34, 80078 Pozzuoli, Naples, Italy.
  • Platt N; Department of Pharmacology, University of Oxford, Oxford, UK.
  • Guida A; Department of Experimental Oncology, European Institute of Oncology, 20139 Milan, Italy.
  • Ogmundsdottir MH; Department of Biochemistry and Molecular Biology, University of Iceland, Vatnsmyrarvegur 16, Reykjavik 101, Iceland.
  • Lanfrancone L; Department of Experimental Oncology, European Institute of Oncology, 20139 Milan, Italy.
  • Perera RM; Department of Anatomy and Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA 94143, USA.
  • Zoncu R; Department of Molecular and Cellular Biology and Paul F. Glenn Center for Aging Research, University of California, Berkeley, Berkeley, CA 94720, USA.
  • Pelicci PG; Department of Experimental Oncology, European Institute of Oncology, 20139 Milan, Italy.
  • Settembre C; Department of Oncology, University of Milan, 20139 Milan, Italy.
  • Ballabio A; Telethon Institute of Genetics and Medicine (TIGEM), Via Campi Flegrei 34, 80078 Pozzuoli, Naples, Italy.
Science ; 356(6343): 1188-1192, 2017 06 16.
Article em En | MEDLINE | ID: mdl-28619945
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Regulação Neoplásica da Expressão Gênica / Retroalimentação Fisiológica / Alvo Mecanístico do Complexo 1 de Rapamicina / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Science Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Itália País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Regulação Neoplásica da Expressão Gênica / Retroalimentação Fisiológica / Alvo Mecanístico do Complexo 1 de Rapamicina / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Science Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Itália País de publicação: Estados Unidos