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Hypoglycemic Coma Induced by the Use of Succinic Acid Cibenzoline in Frail Late-stage Elderly Subjects.
Hirata, Yurie; Kamei, Shinji; Tatsumi, Fuminori; Shimoda, Masashi; Tanabe, Akihito; Sanada, Junpei; Fushimi, Yoshiro; Irie, Shintaro; Mune, Tomoatsu; Kaku, Kohei; Kaneto, Hideaki.
Afiliação
  • Hirata Y; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Japan.
  • Kamei S; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Japan.
  • Tatsumi F; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Japan.
  • Shimoda M; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Japan.
  • Tanabe A; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Japan.
  • Sanada J; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Japan.
  • Fushimi Y; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Japan.
  • Irie S; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Japan.
  • Mune T; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Japan.
  • Kaku K; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Japan.
  • Kaneto H; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Japan.
Intern Med ; 56(12): 1527-1529, 2017.
Article em En | MEDLINE | ID: mdl-28626178
ABSTRACT
Succinic acid cibenzoline (CZ) is an antiarrhythmic agent often used for the treatment of tachyarrhythmia. However, hypoglycemia should be avoided in the treatment of diabetes. We herein report two late-stage elderly subjects who experienced a severe and prolonged hypoglycemic coma after the usage of CZ. These cases suggest that, when CZ is administered to elderly subjects with renal dysfunction and/or frailty, we should be aware of the possibility that this medicine may induce hypoglycemia and should adjust the dose as appropriate and monitor the concentration of CZ to avoid severe hypoglycemia.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Coma / Hipoglicemia / Imidazóis / Antiarrítmicos Limite: Aged80 / Female / Humans / Male Idioma: En Revista: Intern Med Assunto da revista: MEDICINA INTERNA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Japão
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Coma / Hipoglicemia / Imidazóis / Antiarrítmicos Limite: Aged80 / Female / Humans / Male Idioma: En Revista: Intern Med Assunto da revista: MEDICINA INTERNA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Japão