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Identification of Three Novel Radiotracers for Imaging Aggregated Tau in Alzheimer's Disease with Positron Emission Tomography.
Gobbi, Luca C; Knust, Henner; Körner, Matthias; Honer, Michael; Czech, Christian; Belli, Sara; Muri, Dieter; Edelmann, Martin R; Hartung, Thomas; Erbsmehl, Isabella; Grall-Ulsemer, Sandra; Koblet, Andreas; Rueher, Marianne; Steiner, Sandra; Ravert, Hayden T; Mathews, William B; Holt, Daniel P; Kuwabara, Hiroto; Valentine, Heather; Dannals, Robert F; Wong, Dean F; Borroni, Edilio.
Afiliação
  • Gobbi LC; Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd. , CH-4070 Basel, Switzerland.
  • Knust H; Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd. , CH-4070 Basel, Switzerland.
  • Körner M; Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd. , CH-4070 Basel, Switzerland.
  • Honer M; Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd. , CH-4070 Basel, Switzerland.
  • Czech C; Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd. , CH-4070 Basel, Switzerland.
  • Belli S; Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd. , CH-4070 Basel, Switzerland.
  • Muri D; Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd. , CH-4070 Basel, Switzerland.
  • Edelmann MR; Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd. , CH-4070 Basel, Switzerland.
  • Hartung T; Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd. , CH-4070 Basel, Switzerland.
  • Erbsmehl I; Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd. , CH-4070 Basel, Switzerland.
  • Grall-Ulsemer S; Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd. , CH-4070 Basel, Switzerland.
  • Koblet A; Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd. , CH-4070 Basel, Switzerland.
  • Rueher M; Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd. , CH-4070 Basel, Switzerland.
  • Steiner S; Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd. , CH-4070 Basel, Switzerland.
  • Borroni E; Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd. , CH-4070 Basel, Switzerland.
J Med Chem ; 60(17): 7350-7370, 2017 09 14.
Article em En | MEDLINE | ID: mdl-28654263
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Radioisótopos de Carbono / Radioisótopos de Flúor / Proteínas tau / Tomografia por Emissão de Pósitrons / Doença de Alzheimer / Agregação Patológica de Proteínas Tipo de estudo: Diagnostic_studies Limite: Animals / Humans / Male Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Suíça
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Radioisótopos de Carbono / Radioisótopos de Flúor / Proteínas tau / Tomografia por Emissão de Pósitrons / Doença de Alzheimer / Agregação Patológica de Proteínas Tipo de estudo: Diagnostic_studies Limite: Animals / Humans / Male Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Suíça