Development of a continuous direct compression platform for low-dose drug products.

Van Snick, B; Holman, J; Vanhoorne, V; Kumar, A; De Beer, T; Remon, J P; Vervaet, C

Van Snick, B; Holman, J; Vanhoorne, V; Kumar, A; De Beer, T; Remon, J P; Vervaet, C.

Afiliação

Van Snick B; Laboratory of Pharmaceutical Technology, Ghent University, Ghent, Belgium.
Holman J; GEA APC Pharma Solids, Eastleigh, United Kingdom.
Vanhoorne V; Laboratory of Pharmaceutical Technology, Ghent University, Ghent, Belgium.
Kumar A; Janssen Research & Development, Janssen Pharmaceutical Companies of Johnson & Johnson, Beerse, Belgium.
De Beer T; Laboratory of Process Analytical Technology, Ghent University, Ghent, Belgium.
Remon JP; Laboratory of Pharmaceutical Technology, Ghent University, Ghent, Belgium.
Vervaet C; Laboratory of Pharmaceutical Technology, Ghent University, Ghent, Belgium. Electronic address: chris.vervaet@ugent.be.

Int J Pharm ; 529(1-2): 329-346, 2017 Aug 30.

Article em En | MEDLINE | ID: mdl-28684361

Assuntos

Química Farmacêutica; Comprimidos; Tecnologia Farmacêutica; Tamanho da Partícula; Pós

Palavras-chave

Continuous direct compression; Continuous manufacturing; Continuous mixing; Process analytical technology; Raw material characterization; Residence time distribution; Twin screw feeding

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Comprimidos / Química Farmacêutica / Tecnologia Farmacêutica Tipo de estudo: Prognostic_studies Idioma: En Revista: Int J Pharm Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Bélgica País de publicação: Holanda

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