[Clinical trials with mercapto polycytidylic acid in the treatment of acute childhood leukemia (author's transl)]. / Behandlungsversuche mit Mercaptopolycytidylsäure bei akuten Leukämien des Kindes.
Klin Padiatr
; 191(2): 152-5, 1979 Mar.
Article
em De
| MEDLINE
| ID: mdl-286846
ABSTRACT
Mercapto Polycytidylic acid (MPC) is a potent inhibitor of oncornaviral reverse transcriptase. The fact that this enzyme has been found in human leukemic cells, has let to the clinical trials of MPC in the treatment of childhood acute leukemia. This report discribes the first pilot clinical trial on 23 patients. The results are encouraging, and have let to a second pilot study including other clinical centers on the clinical efficacy of MPC in the treatment of leukemia.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Poli C
/
Polirribonucleotídeos
/
Leucemia
Limite:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Idioma:
De
Revista:
Klin Padiatr
Ano de publicação:
1979
Tipo de documento:
Article