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Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening.
Machutta, Carl A; Kollmann, Christopher S; Lind, Kenneth E; Bai, Xiaopeng; Chan, Pan F; Huang, Jianzhong; Ballell, Lluis; Belyanskaya, Svetlana; Besra, Gurdyal S; Barros-Aguirre, David; Bates, Robert H; Centrella, Paolo A; Chang, Sandy S; Chai, Jing; Choudhry, Anthony E; Coffin, Aaron; Davie, Christopher P; Deng, Hongfeng; Deng, Jianghe; Ding, Yun; Dodson, Jason W; Fosbenner, David T; Gao, Enoch N; Graham, Taylor L; Graybill, Todd L; Ingraham, Karen; Johnson, Walter P; King, Bryan W; Kwiatkowski, Christopher R; Lelièvre, Joël; Li, Yue; Liu, Xiaorong; Lu, Quinn; Lehr, Ruth; Mendoza-Losana, Alfonso; Martin, John; McCloskey, Lynn; McCormick, Patti; O'Keefe, Heather P; O'Keeffe, Thomas; Pao, Christina; Phelps, Christopher B; Qi, Hongwei; Rafferty, Keith; Scavello, Genaro S; Steiginga, Matt S; Sundersingh, Flora S; Sweitzer, Sharon M; Szewczuk, Lawrence M; Taylor, Amy.
Afiliação
  • Machutta CA; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, USA.
  • Kollmann CS; GlaxoSmithKline, 830 Winter Street, Waltham, Massachusetts 02451, USA.
  • Lind KE; GlaxoSmithKline, 830 Winter Street, Waltham, Massachusetts 02451, USA.
  • Bai X; GlaxoSmithKline, 830 Winter Street, Waltham, Massachusetts 02451, USA.
  • Chan PF; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, USA.
  • Huang J; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, USA.
  • Ballell L; GlaxoSmithKline, Severo Ochoa 2, Tres Cantos, Madrid 28760, Spain.
  • Belyanskaya S; GlaxoSmithKline, 830 Winter Street, Waltham, Massachusetts 02451, USA.
  • Besra GS; University of Birmingham, School of Biosciences, Edgbaston, Birmingham B15 2TT, UK.
  • Barros-Aguirre D; GlaxoSmithKline, Severo Ochoa 2, Tres Cantos, Madrid 28760, Spain.
  • Bates RH; GlaxoSmithKline, Severo Ochoa 2, Tres Cantos, Madrid 28760, Spain.
  • Centrella PA; GlaxoSmithKline, 830 Winter Street, Waltham, Massachusetts 02451, USA.
  • Chang SS; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, USA.
  • Chai J; GlaxoSmithKline, 830 Winter Street, Waltham, Massachusetts 02451, USA.
  • Choudhry AE; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, USA.
  • Coffin A; GlaxoSmithKline, 830 Winter Street, Waltham, Massachusetts 02451, USA.
  • Davie CP; GlaxoSmithKline, 830 Winter Street, Waltham, Massachusetts 02451, USA.
  • Deng H; GlaxoSmithKline, 830 Winter Street, Waltham, Massachusetts 02451, USA.
  • Deng J; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, USA.
  • Ding Y; GlaxoSmithKline, 830 Winter Street, Waltham, Massachusetts 02451, USA.
  • Dodson JW; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, USA.
  • Fosbenner DT; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, USA.
  • Gao EN; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, USA.
  • Graham TL; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, USA.
  • Graybill TL; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, USA.
  • Ingraham K; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, USA.
  • Johnson WP; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, USA.
  • King BW; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, USA.
  • Kwiatkowski CR; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, USA.
  • Lelièvre J; GlaxoSmithKline, Severo Ochoa 2, Tres Cantos, Madrid 28760, Spain.
  • Li Y; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, USA.
  • Liu X; GlaxoSmithKline, 830 Winter Street, Waltham, Massachusetts 02451, USA.
  • Lu Q; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, USA.
  • Lehr R; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, USA.
  • Mendoza-Losana A; GlaxoSmithKline, Severo Ochoa 2, Tres Cantos, Madrid 28760, Spain.
  • Martin J; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, USA.
  • McCloskey L; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, USA.
  • McCormick P; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, USA.
  • O'Keefe HP; GlaxoSmithKline, 830 Winter Street, Waltham, Massachusetts 02451, USA.
  • O'Keeffe T; GlaxoSmithKline, 830 Winter Street, Waltham, Massachusetts 02451, USA.
  • Pao C; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, USA.
  • Phelps CB; GlaxoSmithKline, 830 Winter Street, Waltham, Massachusetts 02451, USA.
  • Qi H; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, USA.
  • Rafferty K; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, USA.
  • Scavello GS; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, USA.
  • Steiginga MS; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, USA.
  • Sundersingh FS; GlaxoSmithKline, 830 Winter Street, Waltham, Massachusetts 02451, USA.
  • Sweitzer SM; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, USA.
  • Szewczuk LM; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, USA.
  • Taylor A; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, USA.
Nat Commun ; 8: 16081, 2017 07 17.
Article em En | MEDLINE | ID: mdl-28714473
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Staphylococcus aureus / Biblioteca Gênica / Acinetobacter baumannii / Bibliotecas de Moléculas Pequenas / Descoberta de Drogas / Antibacterianos / Mycobacterium tuberculosis Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Staphylococcus aureus / Biblioteca Gênica / Acinetobacter baumannii / Bibliotecas de Moléculas Pequenas / Descoberta de Drogas / Antibacterianos / Mycobacterium tuberculosis Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido