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IKKß inhibition prevents fat-induced beta cell dysfunction in vitro and in vivo in rodents.
Ivovic, Aleksandar; Oprescu, Andrei I; Koulajian, Khajag; Mori, Yusaku; Eversley, Judith A; Zhang, Liling; Nino-Fong, Rodolfo; Lewis, Gary F; Donath, Marc Y; Karin, Michael; Wheeler, Michael B; Ehses, Jan; Volchuk, Allen; Chan, Catherine B; Giacca, Adria.
Afiliação
  • Ivovic A; Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, ON, Canada, M5S 1A8.
  • Oprescu AI; Institute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
  • Koulajian K; Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, ON, Canada, M5S 1A8.
  • Mori Y; Division of Diabetes, Metabolism, and Endocrinology, Showa University School of Medicine, Shinagawa, Tokyo, Japan.
  • Eversley JA; Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, ON, Canada, M5S 1A8.
  • Zhang L; Division of Cellular and Molecular Biology, Toronto General Research Institute, University Health Network, Toronto, ON, Canada.
  • Nino-Fong R; Department of Biomedical Sciences, Ross University School of Veterinary Medicine, Basseterre, St Kitts and Nevis.
  • Lewis GF; Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, ON, Canada, M5S 1A8.
  • Donath MY; Department of Medicine, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
  • Karin M; Banting and Best Diabetes Centre, University of Toronto, Toronto, ON, Canada.
  • Wheeler MB; Department of Endocrinology, Diabetes, and Metabolism, University Hospital Basel, Basel, Switzerland.
  • Ehses J; Department of Pharmacology, University of California, San Diego, School of Medicine, La Jolla, CA, USA.
  • Volchuk A; Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, ON, Canada, M5S 1A8.
  • Chan CB; Department of Surgery, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.
  • Giacca A; Child and Family Research Institute, Vancouver, BC, Canada.
Diabetologia ; 60(10): 2021-2032, 2017 10.
Article em En | MEDLINE | ID: mdl-28725915

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácido Oleico / Ácido Salicílico / Células Secretoras de Insulina / Quinase I-kappa B / Ácidos Graxos não Esterificados Limite: Animals Idioma: En Revista: Diabetologia Ano de publicação: 2017 Tipo de documento: Article País de publicação: Alemanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácido Oleico / Ácido Salicílico / Células Secretoras de Insulina / Quinase I-kappa B / Ácidos Graxos não Esterificados Limite: Animals Idioma: En Revista: Diabetologia Ano de publicação: 2017 Tipo de documento: Article País de publicação: Alemanha