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A Novel Selective Inverse Agonist of the CB2 Receptor as a Radiolabeled Tool Compound for Kinetic Binding Studies.
Martella, Andrea; Sijben, Huub; Rufer, Arne C; Grether, Uwe; Fingerle, Juergen; Ullmer, Christoph; Hartung, Thomas; IJzerman, Adriaan P; van der Stelt, Mario; Heitman, Laura H.
Afiliação
  • Martella A; Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research (A.M., H.S., A.P.I., L.H.H.), and Department of Molecular Physiology, Leiden Institute of Chemistry (A.M., M.S.), Leiden University, Leiden, The Netherlands; Roche Pharma Research and Early Development, Roche Innovation Center
  • Sijben H; Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research (A.M., H.S., A.P.I., L.H.H.), and Department of Molecular Physiology, Leiden Institute of Chemistry (A.M., M.S.), Leiden University, Leiden, The Netherlands; Roche Pharma Research and Early Development, Roche Innovation Center
  • Rufer AC; Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research (A.M., H.S., A.P.I., L.H.H.), and Department of Molecular Physiology, Leiden Institute of Chemistry (A.M., M.S.), Leiden University, Leiden, The Netherlands; Roche Pharma Research and Early Development, Roche Innovation Center
  • Grether U; Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research (A.M., H.S., A.P.I., L.H.H.), and Department of Molecular Physiology, Leiden Institute of Chemistry (A.M., M.S.), Leiden University, Leiden, The Netherlands; Roche Pharma Research and Early Development, Roche Innovation Center
  • Fingerle J; Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research (A.M., H.S., A.P.I., L.H.H.), and Department of Molecular Physiology, Leiden Institute of Chemistry (A.M., M.S.), Leiden University, Leiden, The Netherlands; Roche Pharma Research and Early Development, Roche Innovation Center
  • Ullmer C; Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research (A.M., H.S., A.P.I., L.H.H.), and Department of Molecular Physiology, Leiden Institute of Chemistry (A.M., M.S.), Leiden University, Leiden, The Netherlands; Roche Pharma Research and Early Development, Roche Innovation Center
  • Hartung T; Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research (A.M., H.S., A.P.I., L.H.H.), and Department of Molecular Physiology, Leiden Institute of Chemistry (A.M., M.S.), Leiden University, Leiden, The Netherlands; Roche Pharma Research and Early Development, Roche Innovation Center
  • IJzerman AP; Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research (A.M., H.S., A.P.I., L.H.H.), and Department of Molecular Physiology, Leiden Institute of Chemistry (A.M., M.S.), Leiden University, Leiden, The Netherlands; Roche Pharma Research and Early Development, Roche Innovation Center
  • van der Stelt M; Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research (A.M., H.S., A.P.I., L.H.H.), and Department of Molecular Physiology, Leiden Institute of Chemistry (A.M., M.S.), Leiden University, Leiden, The Netherlands; Roche Pharma Research and Early Development, Roche Innovation Center
  • Heitman LH; Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research (A.M., H.S., A.P.I., L.H.H.), and Department of Molecular Physiology, Leiden Institute of Chemistry (A.M., M.S.), Leiden University, Leiden, The Netherlands; Roche Pharma Research and Early Development, Roche Innovation Center
Mol Pharmacol ; 92(4): 389-400, 2017 10.
Article em En | MEDLINE | ID: mdl-28747489
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Canabinoides / Receptor CB2 de Canabinoide / Agonismo Inverso de Drogas Limite: Animals / Humans Idioma: En Revista: Mol Pharmacol Ano de publicação: 2017 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Canabinoides / Receptor CB2 de Canabinoide / Agonismo Inverso de Drogas Limite: Animals / Humans Idioma: En Revista: Mol Pharmacol Ano de publicação: 2017 Tipo de documento: Article País de publicação: Estados Unidos