Massive Accumulation of Myofibroblasts in the Critical Isthmus Is Associated With Ventricular Tachycardia Inducibility in Post-Infarct Swine Heart.

Dhanjal, Tarvinder S; Lellouche, Nicolas; von Ruhland, Christopher J; Abehsira, Guillaume; Edwards, David H; Dubois-Randé, Jean-Luc; Moschonas, Konstantinos; Teiger, Emmanuel; Williams, Alan J; George, Christopher H

Massive Accumulation of Myofibroblasts in the Critical Isthmus Is Associated With Ventricular Tachycardia Inducibility in Post-Infarct Swine Heart.

Dhanjal, Tarvinder S; Lellouche, Nicolas; von Ruhland, Christopher J; Abehsira, Guillaume; Edwards, David H; Dubois-Randé, Jean-Luc; Moschonas, Konstantinos; Teiger, Emmanuel; Williams, Alan J; George, Christopher H.

Afiliação

Dhanjal TS; School of Medicine, Cardiff University, Cardiff, Wales, United Kingdom.
Lellouche N; Hôpital Henri Mondor Albert Chenevier, DHU-ATVB, Inserm U955, IMRB, University Paris Est Creteil Paris XII, Paris, France.
von Ruhland CJ; Hôpital Henri Mondor Albert Chenevier, DHU-ATVB, Inserm U955, IMRB, University Paris Est Creteil Paris XII, Paris, France.
Abehsira G; School of Medicine, Cardiff University, Cardiff, Wales, United Kingdom.
Edwards DH; Hôpital Henri Mondor Albert Chenevier, DHU-ATVB, Inserm U955, IMRB, University Paris Est Creteil Paris XII, Paris, France.
Dubois-Randé JL; School of Medicine, Cardiff University, Cardiff, Wales, United Kingdom.
Moschonas K; Institute of Life Sciences, Swansea University Medical School, Swansea, Wales, United Kingdom.
Teiger E; Hôpital Henri Mondor Albert Chenevier, DHU-ATVB, Inserm U955, IMRB, University Paris Est Creteil Paris XII, Paris, France.
Williams AJ; School of Medicine, Cardiff University, Cardiff, Wales, United Kingdom.
George CH; Hôpital Henri Mondor Albert Chenevier, DHU-ATVB, Inserm U955, IMRB, University Paris Est Creteil Paris XII, Paris, France.

JACC Clin Electrophysiol ; 3(7): 703-714, 2017 07.

Article em En | MEDLINE | ID: mdl-28770255

Assuntos

Infarto do Miocárdio/complicações; Miofibroblastos/patologia; Taquicardia Ventricular/etiologia; Animais; Modelos Animais de Doenças; Mapeamento Epicárdico; Feminino; Infarto do Miocárdio/patologia; Infarto do Miocárdio/fisiopatologia; Suínos; Taquicardia Ventricular/patologia; Taquicardia Ventricular/fisiopatologia

Palavras-chave

BZ, border zone; CI, critical isthmus; CM, cardiomyocytes; ECM, extracellular matrix; EP, electrophysiology; FB, fibroblasts; IHC, immunohistochemistry; LAD, left anterior descending; LAVA, local abnormal ventricular activity; MFB, myofibroblasts; MI, myocardial infarction; MRI, magnetic resonance imaging; VT; VT, ventricular tachycardia; Vim, vimentin; border zone; cTnT, cardiac troponin T; critical isthmus; iVT, inducible ventricular tachycardia; myocardial infarction; myofibroblasts; pig; vWF, von Willebrand factor; α-SMA, α-smooth muscle actin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Taquicardia Ventricular / Miofibroblastos / Infarto do Miocárdio Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: JACC Clin Electrophysiol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos

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