The analgesic activities of Stauntonia brachyanthera and YM<sub>11</sub> through regulating inflammatory mediators and directly controlling the sodium channel prompt.

Meng, Dali; Wang, Lei; Du, Jingnan; Chen, Jianchao; Chen, Chao; Xu, Wei; Li, Chunli

The analgesic activities of Stauntonia brachyanthera and YM₁₁ through regulating inflammatory mediators and directly controlling the sodium channel prompt.

Meng, Dali; Wang, Lei; Du, Jingnan; Chen, Jianchao; Chen, Chao; Xu, Wei; Li, Chunli.

Afiliação

Meng D; Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University), Ministry of Education; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, 110016, PR China.
Wang L; Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University), Ministry of Education; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, 110016, PR China.
Du J; School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, 110016, PR China.
Chen J; School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, 110016, PR China.
Chen C; Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University), Ministry of Education; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, 110016, PR China.
Xu W; Shanghai Star Pharm Co., Ltd, Shanghai, 201318, PR China.
Li C; Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University), Ministry of Education; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, 110016, PR China.

Sci Rep ; 7(1): 7574, 2017 08 08.

Article em En | MEDLINE | ID: mdl-28790377

Assuntos

Analgésicos/farmacologia; Mediadores da Inflamação/antagonistas & inibidores; Canal de Sódio Disparado por Voltagem NAV1.8/efeitos dos fármacos; Canal de Sódio Disparado por Voltagem NAV1.8/metabolismo; Extratos Vegetais/farmacologia; Ranunculales/química; Analgésicos/isolamento & purificação; Animais; Gânglios Espinais/efeitos dos fármacos; Camundongos; Neurônios/efeitos dos fármacos; Extratos Vegetais/isolamento & purificação; Ratos

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Mediadores da Inflamação / Canal de Sódio Disparado por Voltagem NAV1.8 / Ranunculales / Analgésicos Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2017 Tipo de documento: Article País de publicação: Reino Unido

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