Obeticholic acid, a selective farnesoid X receptor agonist, regulates bile acid homeostasis in sandwich-cultured human hepatocytes.

Zhang, Yuanyuan; Jackson, Jonathan P; St Claire, Robert L; Freeman, Kimberly; Brouwer, Kenneth R; Edwards, Jeffrey E

Zhang, Yuanyuan; Jackson, Jonathan P; St Claire, Robert L; Freeman, Kimberly; Brouwer, Kenneth R; Edwards, Jeffrey E.

Afiliação

Zhang Y; Intercept Pharmaceuticals Inc., San Diego, California.
Jackson JP; Qualyst Transporter Solutions, Durham, North Carolina.
St Claire RL; Qualyst Transporter Solutions, Durham, North Carolina.
Freeman K; Qualyst Transporter Solutions, Durham, North Carolina.
Brouwer KR; Qualyst Transporter Solutions, Durham, North Carolina.
Edwards JE; Intercept Pharmaceuticals Inc., San Diego, California.

Pharmacol Res Perspect ; 5(4)2017 Aug.

Article em En | MEDLINE | ID: mdl-28805978

Palavras-chave

FXR; OCA; Cholestatic disease; Farnesoid X receptor; bile acid; homeostasis; obeticholic acid

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Pharmacol Res Perspect Ano de publicação: 2017 Tipo de documento: Article País de publicação: Estados Unidos

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