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IncX3 plasmid harboring a non-Tn4401 genetic element (NTEKPC) in a hospital-associated clone of KPC-2-producing Klebsiella pneumoniae ST340/CG258.
Cerdeira, Louise T; Cunha, Marcos P V; Francisco, Gabriela R; Bueno, Maria Fernanda C; Araujo, Bruna F; Ribas, Rosineide M; Gontijo-Filho, Paulo P; Knöbl, Terezinha; de Oliveira Garcia, Doroti; Lincopan, Nilton.
Afiliação
  • Cerdeira LT; Department of Clinical Analysis, School of Pharmacy, Universidade de São Paulo, São Paulo, Brazil.
  • Cunha MPV; School of Veterinary Medicine, University of São Paulo, São Paulo, Brazil.
  • Francisco GR; Center of Bacteriology, Instituto Adolfo Lutz, São Paulo, Brazil.
  • Bueno MFC; Center of Bacteriology, Instituto Adolfo Lutz, São Paulo, Brazil.
  • Araujo BF; Institute of Biomedical Sciences, Federal University of Uberlandia, Uberlandia, Minas Gerais, Brazil.
  • Ribas RM; Institute of Biomedical Sciences, Federal University of Uberlandia, Uberlandia, Minas Gerais, Brazil.
  • Gontijo-Filho PP; Institute of Biomedical Sciences, Federal University of Uberlandia, Uberlandia, Minas Gerais, Brazil.
  • Knöbl T; School of Veterinary Medicine, University of São Paulo, São Paulo, Brazil.
  • de Oliveira Garcia D; Center of Bacteriology, Instituto Adolfo Lutz, São Paulo, Brazil.
  • Lincopan N; Department of Clinical Analysis, School of Pharmacy, Universidade de São Paulo, São Paulo, Brazil; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil. Electronic address: lincopan@usp.br.
Diagn Microbiol Infect Dis ; 89(2): 164-167, 2017 Oct.
Article em En | MEDLINE | ID: mdl-28807400
ABSTRACT
IncX-type plasmids have achieved clinical significance for their contribution in the dissemination of genes confering resistance to carbapenems (most blaKPC- and blaNDM-type genes) and polymyxins (mcr-type genes), both antibiotics considered last resort for multidrug-resistant Gram-negative infections. In this study, we report the identification and complete sequence analysis of an IncX3 plasmid (designated pKP1194a) carrying a non-Tn4401 genetic element (NTEKPC) of tnpR-tnpA (partial)-blaKPC-2-ΔISKpn6/traN, originating from a hospital-associated lineage of K. pneumoniae belonging to the ST340/CG258, with epidemiological link to Brazil.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plasmídeos / Beta-Lactamases / Sequências Repetitivas Dispersas / Farmacorresistência Bacteriana Múltipla / Klebsiella pneumoniae Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Revista: Diagn Microbiol Infect Dis Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Brasil
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plasmídeos / Beta-Lactamases / Sequências Repetitivas Dispersas / Farmacorresistência Bacteriana Múltipla / Klebsiella pneumoniae Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Revista: Diagn Microbiol Infect Dis Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Brasil