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A Loss-of-Function Splice Acceptor Variant in IGF2 Is Protective for Type 2 Diabetes.
Mercader, Josep M; Liao, Rachel G; Bell, Avery D; Dymek, Zachary; Estrada, Karol; Tukiainen, Taru; Huerta-Chagoya, Alicia; Moreno-Macías, Hortensia; Jablonski, Kathleen A; Hanson, Robert L; Walford, Geoffrey A; Moran, Ignasi; Chen, Ling; Agarwala, Vineeta; Ordoñez-Sánchez, María Luisa; Rodríguez-Guillen, Rosario; Rodríguez-Torres, Maribel; Segura-Kato, Yayoi; García-Ortiz, Humberto; Centeno-Cruz, Federico; Barajas-Olmos, Francisco; Caulkins, Lizz; Puppala, Sobha; Fontanillas, Pierre; Williams, Amy L; Bonàs-Guarch, Sílvia; Hartl, Chris; Ripke, Stephan; Tooley, Katherine; Lane, Jacqueline; Zerrweck, Carlos; Martínez-Hernández, Angélica; Córdova, Emilio J; Mendoza-Caamal, Elvia; Contreras-Cubas, Cecilia; González-Villalpando, María E; Cruz-Bautista, Ivette; Muñoz-Hernández, Liliana; Gómez-Velasco, Donaji; Alvirde, Ulises; Henderson, Brian E; Wilkens, Lynne R; Le Marchand, Loic; Arellano-Campos, Olimpia; Riba, Laura; Harden, Maegan; Gabriel, Stacey; Abboud, Hanna E; Cortes, Maria L; Revilla-Monsalve, Cristina.
Afiliação
  • Mercader JM; Broad Metabolism Program and Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.
  • Liao RG; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA.
  • Bell AD; Barcelona Supercomputing Center, Joint BSC-CRG-IRB Research Programme in Computational Biology, Barcelona, Spain.
  • Dymek Z; Broad Metabolism Program and Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.
  • Estrada K; Department of Genetics, Harvard Medical School, Boston, MA.
  • Tukiainen T; Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA.
  • Huerta-Chagoya A; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.
  • Moreno-Macías H; Broad Metabolism Program and Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.
  • Jablonski KA; Broad Metabolism Program and Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.
  • Hanson RL; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA.
  • Walford GA; Department of Medicine, Harvard Medical School, Boston, MA.
  • Moran I; Department of Genetics, Harvard Medical School, Boston, MA.
  • Chen L; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.
  • Agarwala V; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA.
  • Ordoñez-Sánchez ML; Consejo Nacional de Ciencia y Tecnología (CONACYT), Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
  • Rodríguez-Guillen R; Unidad de Biología Molecular y Medicina Genómica, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México/Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
  • Rodríguez-Torres M; Universidad Autónoma Metropolitana, Mexico City, Mexico.
  • Segura-Kato Y; The Biostatistics Center, The George Washington University, Rockville, MD.
  • García-Ortiz H; Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, AZ.
  • Centeno-Cruz F; Broad Metabolism Program and Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.
  • Barajas-Olmos F; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA.
  • Caulkins L; Department of Medicine, Harvard Medical School, Boston, MA.
  • Puppala S; Department of Medicine, Imperial College London, London, U.K.
  • Fontanillas P; Broad Metabolism Program and Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.
  • Williams AL; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA.
  • Bonàs-Guarch S; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.
  • Hartl C; Consejo Nacional de Ciencia y Tecnología (CONACYT), Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
  • Ripke S; Consejo Nacional de Ciencia y Tecnología (CONACYT), Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
  • Tooley K; Consejo Nacional de Ciencia y Tecnología (CONACYT), Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
  • Lane J; Instituto Nacional de Medicina Genómica, Mexico City, Mexico.
  • Zerrweck C; Instituto Nacional de Medicina Genómica, Mexico City, Mexico.
  • Martínez-Hernández A; Instituto Nacional de Medicina Genómica, Mexico City, Mexico.
  • Córdova EJ; Broad Metabolism Program and Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.
  • Mendoza-Caamal E; Department of Genetics, Texas Biomedical Research Institute, San Antonio, TX.
  • Contreras-Cubas C; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.
  • González-Villalpando ME; Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, NY.
  • Cruz-Bautista I; Barcelona Supercomputing Center, Joint BSC-CRG-IRB Research Programme in Computational Biology, Barcelona, Spain.
  • Muñoz-Hernández L; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.
  • Gómez-Velasco D; Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA.
  • Alvirde U; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA.
  • Henderson BE; Department of Psychiatry and Psychotherapy, Charité-Universitätsmedizin Berlin, Berlin, Germany.
  • Le Marchand L; Department of Genetics, Harvard Medical School, Boston, MA.
  • Arellano-Campos O; Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA.
  • Riba L; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.
  • Harden M; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.
  • Gabriel S; Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA.
  • Abboud HE; Instituto Nacional de Medicina Genómica, Mexico City, Mexico.
  • Cortes ML; Instituto Nacional de Medicina Genómica, Mexico City, Mexico.
  • Revilla-Monsalve C; Instituto Nacional de Medicina Genómica, Mexico City, Mexico.
Diabetes ; 66(11): 2903-2914, 2017 11.
Article em En | MEDLINE | ID: mdl-28838971
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de Crescimento Insulin-Like II / Sítios de Splice de RNA / Diabetes Mellitus Tipo 2 Tipo de estudo: Prognostic_studies Limite: Humans País/Região como assunto: Mexico Idioma: En Revista: Diabetes Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Marrocos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de Crescimento Insulin-Like II / Sítios de Splice de RNA / Diabetes Mellitus Tipo 2 Tipo de estudo: Prognostic_studies Limite: Humans País/Região como assunto: Mexico Idioma: En Revista: Diabetes Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Marrocos