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A rectal cancer feasibility study with an embedded phase III trial design assessing magnetic resonance tumour regression grade (mrTRG) as a novel biomarker to stratify management by good and poor response to chemoradiotherapy (TRIGGER): study protocol for a randomised controlled trial.
Battersby, Nick J; Dattani, Mit; Rao, Sheela; Cunningham, David; Tait, Diana; Adams, Richard; Moran, Brendan J; Khakoo, Shelize; Tekkis, Paris; Rasheed, Shahnawaz; Mirnezami, Alex; Quirke, Philip; West, Nicholas P; Nagtegaal, Iris; Chong, Irene; Sadanandam, Anguraj; Valeri, Nicola; Thomas, Karen; Frost, Michelle; Brown, Gina.
Afiliação
  • Battersby NJ; Pelican Cancer Foundation, The Ark, Basingstoke, RG24 9NN, UK.
  • Dattani M; North Hampshire Hospital Foundation Trust, Basingstoke, RG24 9NA, UK.
  • Rao S; Pelican Cancer Foundation, The Ark, Basingstoke, RG24 9NN, UK.
  • Cunningham D; Department of Medicine Royal Marsden Hospital Sutton, Sutton, SM2 5PT, UK.
  • Tait D; Department of Medicine Royal Marsden Hospital Sutton, Sutton, SM2 5PT, UK.
  • Adams R; Department of Medicine Royal Marsden Hospital Sutton, Sutton, SM2 5PT, UK.
  • Moran BJ; Velindre Cancer Centre Velindre Hospital Cardiff, Cardiff, CF4 7XL, UK.
  • Khakoo S; Pelican Cancer Foundation, The Ark, Basingstoke, RG24 9NN, UK.
  • Tekkis P; North Hampshire Hospital Foundation Trust, Basingstoke, RG24 9NA, UK.
  • Rasheed S; Gastrointestinal Unit Royal Marsden Hospital Sutton, Sutton, SM2 5PT, UK.
  • Mirnezami A; Department of Colorectal Surgery, Royal Marsden Hospital London, London, SW3 6JJ, UK.
  • Quirke P; Department of Colorectal Surgery, Royal Marsden Hospital London, London, SW3 6JJ, UK.
  • West NP; Department of Surgery and Department for Tissue Microarray analysis, University of Southampton, Southampton, SO16 6YD, UK.
  • Nagtegaal I; Pathology and Tumour Biology, Leeds Institute of Cancer and Pathology, Wellcome Trust Brenner Building, St. James's University Hospital, Leeds, LS9 7TF, UK.
  • Chong I; Pathology and Tumour Biology, Leeds Institute of Cancer and Pathology, Wellcome Trust Brenner Building, St. James's University Hospital, Leeds, LS9 7TF, UK.
  • Sadanandam A; Department of Pathology Radboud University, Nijmegen, 6500HB, Netherlands.
  • Valeri N; Division of Molecular Pathology Institute of Cancer Research, London, SW3 6JB, UK.
  • Thomas K; Division of Molecular Pathology Institute of Cancer Research, London, SW3 6JB, UK.
  • Frost M; Division of Molecular Pathology Institute of Cancer Research, London, SW3 6JB, UK.
  • Brown G; Statistics Unit, R&D Royal Marsden Hospital Sutton, Sutton, SM2 5PT, UK.
Trials ; 18(1): 394, 2017 08 29.
Article em En | MEDLINE | ID: mdl-28851403
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Retais / Imageamento por Ressonância Magnética / Adenocarcinoma / Terapia Neoadjuvante / Quimiorradioterapia Adjuvante Tipo de estudo: Clinical_trials / Guideline / Prognostic_studies Aspecto: Patient_preference Limite: Humans Idioma: En Revista: Trials Assunto da revista: MEDICINA / TERAPEUTICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Retais / Imageamento por Ressonância Magnética / Adenocarcinoma / Terapia Neoadjuvante / Quimiorradioterapia Adjuvante Tipo de estudo: Clinical_trials / Guideline / Prognostic_studies Aspecto: Patient_preference Limite: Humans Idioma: En Revista: Trials Assunto da revista: MEDICINA / TERAPEUTICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido