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Discovery of stimulation-responsive immune enhancers with CRISPR activation.
Simeonov, Dimitre R; Gowen, Benjamin G; Boontanrart, Mandy; Roth, Theodore L; Gagnon, John D; Mumbach, Maxwell R; Satpathy, Ansuman T; Lee, Youjin; Bray, Nicolas L; Chan, Alice Y; Lituiev, Dmytro S; Nguyen, Michelle L; Gate, Rachel E; Subramaniam, Meena; Li, Zhongmei; Woo, Jonathan M; Mitros, Therese; Ray, Graham J; Curie, Gemma L; Naddaf, Nicki; Chu, Julia S; Ma, Hong; Boyer, Eric; Van Gool, Frederic; Huang, Hailiang; Liu, Ruize; Tobin, Victoria R; Schumann, Kathrin; Daly, Mark J; Farh, Kyle K; Ansel, K Mark; Ye, Chun J; Greenleaf, William J; Anderson, Mark S; Bluestone, Jeffrey A; Chang, Howard Y; Corn, Jacob E; Marson, Alexander.
Afiliação
  • Simeonov DR; Biomedical Sciences Graduate Program, University of California, San Francisco, California 94143, USA.
  • Gowen BG; Department of Microbiology and Immunology, University of California, San Francisco, California 94143, USA.
  • Boontanrart M; Diabetes Center, University of California, San Francisco, California 94143, USA.
  • Roth TL; Innovative Genomics Institute, University of California, Berkeley, California 94720, USA.
  • Gagnon JD; Innovative Genomics Institute, University of California, Berkeley, California 94720, USA.
  • Mumbach MR; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California 94720, USA.
  • Satpathy AT; Innovative Genomics Institute, University of California, Berkeley, California 94720, USA.
  • Lee Y; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California 94720, USA.
  • Bray NL; Biomedical Sciences Graduate Program, University of California, San Francisco, California 94143, USA.
  • Chan AY; Department of Microbiology and Immunology, University of California, San Francisco, California 94143, USA.
  • Lituiev DS; Diabetes Center, University of California, San Francisco, California 94143, USA.
  • Nguyen ML; Innovative Genomics Institute, University of California, Berkeley, California 94720, USA.
  • Gate RE; Biomedical Sciences Graduate Program, University of California, San Francisco, California 94143, USA.
  • Subramaniam M; Department of Microbiology and Immunology, University of California, San Francisco, California 94143, USA.
  • Li Z; Sandler Asthma Basic Research Center, University of California, San Francisco, California 94143, USA.
  • Woo JM; Center for Personal Dynamic Regulomes, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Mitros T; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Ray GJ; Department of Genetics, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Curie GL; Center for Personal Dynamic Regulomes, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Naddaf N; Department of Genetics, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Chu JS; Department of Microbiology and Immunology, University of California, San Francisco, California 94143, USA.
  • Ma H; Diabetes Center, University of California, San Francisco, California 94143, USA.
  • Boyer E; Innovative Genomics Institute, University of California, Berkeley, California 94720, USA.
  • Van Gool F; Innovative Genomics Institute, University of California, Berkeley, California 94720, USA.
  • Huang H; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California 94720, USA.
  • Liu R; Diabetes Center, University of California, San Francisco, California 94143, USA.
  • Tobin VR; Department of Pediatrics, University of California, San Francisco, California 94143, USA.
  • Schumann K; Department of Epidemiology and Biostatistics, Department of Bioengineering and Therapeutic Sciences, Institute for Human Genetics (IHG), University of California, San Francisco, California 94143, USA.
  • Daly MJ; Department of Microbiology and Immunology, University of California, San Francisco, California 94143, USA.
  • Farh KK; Diabetes Center, University of California, San Francisco, California 94143, USA.
  • Ansel KM; Innovative Genomics Institute, University of California, Berkeley, California 94720, USA.
  • Ye CJ; Department of Epidemiology and Biostatistics, Department of Bioengineering and Therapeutic Sciences, Institute for Human Genetics (IHG), University of California, San Francisco, California 94143, USA.
  • Greenleaf WJ; Biological and Medical Informatics Graduate Program, University of California, San Francisco, California 94158, USA.
  • Anderson MS; Department of Epidemiology and Biostatistics, Department of Bioengineering and Therapeutic Sciences, Institute for Human Genetics (IHG), University of California, San Francisco, California 94143, USA.
  • Bluestone JA; Biological and Medical Informatics Graduate Program, University of California, San Francisco, California 94158, USA.
  • Chang HY; Department of Microbiology and Immunology, University of California, San Francisco, California 94143, USA.
  • Corn JE; Diabetes Center, University of California, San Francisco, California 94143, USA.
  • Marson A; Innovative Genomics Institute, University of California, Berkeley, California 94720, USA.
Nature ; 549(7670): 111-115, 2017 09 07.
Article em En | MEDLINE | ID: mdl-28854172
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autoimunidade / Elementos Facilitadores Genéticos / Repetições Palindrômicas Curtas Agrupadas e Regularmente Espaçadas / Sistemas CRISPR-Cas Limite: Animals / Female / Humans Idioma: En Revista: Nature Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autoimunidade / Elementos Facilitadores Genéticos / Repetições Palindrômicas Curtas Agrupadas e Regularmente Espaçadas / Sistemas CRISPR-Cas Limite: Animals / Female / Humans Idioma: En Revista: Nature Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido