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Macitentan for the treatment of inoperable chronic thromboembolic pulmonary hypertension (MERIT-1): results from the multicentre, phase 2, randomised, double-blind, placebo-controlled study.
Ghofrani, Hossein-Ardeschir; Simonneau, Gérald; D'Armini, Andrea M; Fedullo, Peter; Howard, Luke S; Jaïs, Xavier; Jenkins, David P; Jing, Zhi-Cheng; Madani, Michael M; Martin, Nicolas; Mayer, Eckhard; Papadakis, Kelly; Richard, Dominik; Kim, Nick H.
Afiliação
  • Ghofrani HA; German Center for Lung Research (DZL), Giessen, Germany; University of Giessen and Marburg Lung Center (UGMLC), Giessen, Germany; Department of Medicine, Imperial College London, London, UK. Electronic address: ardeschir.ghofrani@innere.med.uni-giessen.de.
  • Simonneau G; Assistance Publique-Hôpitaux de Paris, Service de Pneumologie, Hôpital Bicêtre, Université Paris-Sud, Laboratoire d'Excellence en Recherche sur le Médicament et Innovation Thérapeutique, Le Kremlin-Bicêtre, France; INSERM U-999, Le Kremlin-Bicêtre, France.
  • D'Armini AM; Department of Cardio-Thoracic and Vascular Surgery, Heart and Lung Transplantation and Pulmonary Hypertension Unit, Foundation IRCCS Policlinico San Matteo, University of Pavia School of Medicine, Pavia, Italy.
  • Fedullo P; Division of Pulmonary and Critical Care Medicine, University of California San Diego, La Jolla, CA, USA.
  • Howard LS; National Pulmonary Hypertension Service, Imperial College Healthcare NHS Trust, Hammersmith Hospital, London, UK; National Heart & Lung Institute, Imperial College London, London, UK.
  • Jaïs X; Assistance Publique-Hôpitaux de Paris, Service de Pneumologie, Hôpital Bicêtre, Université Paris-Sud, Laboratoire d'Excellence en Recherche sur le Médicament et Innovation Thérapeutique, Le Kremlin-Bicêtre, France; INSERM U-999, Le Kremlin-Bicêtre, France.
  • Jenkins DP; Department of Cardiothoracic Surgery, Papworth Hospital, Cambridge, UK.
  • Jing ZC; State Key Lab of Cardiovascular Disease, FuWai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
  • Madani MM; Division of Cardiovascular and Thoracic Surgery, University of California San Diego Medical Center, San Diego, CA, USA.
  • Martin N; Actelion Pharmaceuticals, Allschwil, Switzerland.
  • Mayer E; Department of Thoracic Surgery, Kerckhoff-Clinic, Bad Nauheim, Germany.
  • Papadakis K; Actelion Pharmaceuticals, Allschwil, Switzerland.
  • Richard D; Actelion Pharmaceuticals, Allschwil, Switzerland.
  • Kim NH; Division of Pulmonary and Critical Care Medicine, University of California San Diego, La Jolla, CA, USA.
Lancet Respir Med ; 5(10): 785-794, 2017 10.
Article em En | MEDLINE | ID: mdl-28919201
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Embolia Pulmonar / Pirimidinas / Sulfonamidas / Antagonistas dos Receptores de Endotelina / Hipertensão Pulmonar Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Respir Med Ano de publicação: 2017 Tipo de documento: Article País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Embolia Pulmonar / Pirimidinas / Sulfonamidas / Antagonistas dos Receptores de Endotelina / Hipertensão Pulmonar Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Respir Med Ano de publicação: 2017 Tipo de documento: Article País de publicação: Reino Unido