Into the eyes of bone marrow-derived mesenchymal stem cells therapy for myocardial infarction and other diseases.
Stem Cell Investig
; 4: 69, 2017.
Article
em En
| MEDLINE
| ID: mdl-28920062
ABSTRACT
Applications of bone marrow-derived mesenchymal stem cells (BM-MSCs) have been documented for diseases occur in the sports system, the central nervous system, the cardiovascular system etc. However, poor viability of donor stem cells after transplantation limits their therapeutic efficiency. Although the autophagy theory has been reported, the underlying mechanisms are still poorly understood. Isolation and culture methods of mesenchymal stem cells are currently concentrate on four ways. Overall, BM-MSCs have both important research significance and clinical application value in cell replacement therapy, gene therapy and reconstruction of tissues as well as organs especially for myocardial infarction (MI). In this article, we review the biological characteristics of BM-MSCs and its research progress especially in MI.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Stem Cell Investig
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
China