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Synthesis, Characterization, Antimicrobial Activity, and Docking Studies of New Triazolic Tripodal Ligands.
Harit, Tarik; Bellaouchi, Reda; Rokni, Yahya; Riahi, Abdelkhalek; Malek, Fouad; Asehraou, Abdeslam.
Afiliação
  • Harit T; Laboratory of Organic, Macromolecular Chemistry and Natural Products - URAC 25, Faculty of Sciences, Mohammed First University, Bd Mohamed VI, BP: 717, Oujda, 60000, Morocco.
  • Bellaouchi R; Laboratory of Biochemistry and Biotechnology, Faculty of Sciences, Mohammed First University, Bd Mohamed VI, BP: 717BP 717, Oujda, 60000, Morocco.
  • Rokni Y; Laboratory of Biochemistry and Biotechnology, Faculty of Sciences, Mohammed First University, Bd Mohamed VI, BP: 717BP 717, Oujda, 60000, Morocco.
  • Riahi A; CNRS UMR 6229, Institut de Chimie Moléculaire de Reims (ICMR)-Groupe Méthodologie en Synthèse Organique, Université de Reims Champagne-Ardenne, Bat. Europol'Agro-Moulin de la Housse, BP 1039, Reims Cedex 2, 51687, France.
  • Malek F; Laboratory of Organic, Macromolecular Chemistry and Natural Products - URAC 25, Faculty of Sciences, Mohammed First University, Bd Mohamed VI, BP: 717, Oujda, 60000, Morocco.
  • Asehraou A; Laboratory of Biochemistry and Biotechnology, Faculty of Sciences, Mohammed First University, Bd Mohamed VI, BP: 717BP 717, Oujda, 60000, Morocco.
Chem Biodivers ; 14(12)2017 Dec.
Article em En | MEDLINE | ID: mdl-28990290
ABSTRACT
The synthesis and characterization of new N-donor bitriazolic tripods were reported. The in vitro antibacterial and antifungal activities of these products were screened against fungal strain (Candida pelliculosa) and against four bacterial strains (Micrococcus luteus, Bacillus subtilis, Listeria innocua, and Escherichia coli). Biological data revealed the effect of the chemical structure on antimicrobial activity. Molecular docking studies of some compounds showed that they could act as inhibitors for the biotin carboxylase enzyme.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Triazóis / Anti-Infecciosos Idioma: En Revista: Chem Biodivers Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Marrocos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Triazóis / Anti-Infecciosos Idioma: En Revista: Chem Biodivers Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Marrocos