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Methyl 3-(3-(4-(2,4,4-Trimethylpentan-2-yl)phenoxy)-propanamido)benzoate as a Novel and Dual Malate Dehydrogenase (MDH) 1/2 Inhibitor Targeting Cancer Metabolism.
Naik, Ravi; Ban, Hyun Seung; Jang, Kyusic; Kim, Inhyub; Xu, Xuezhen; Harmalkar, Dipesh; Shin, Seong-Ah; Kim, Minkyoung; Kim, Bo-Kyung; Park, Jaehyung; Ku, Bonsu; Oh, Sujin; Won, Misun; Lee, Kyeong.
Afiliação
  • Naik R; College of Pharmacy, Dongguk University , Goyang 10326, Korea.
  • Ban HS; Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology , Daejeon 34141, Korea.
  • Jang K; Biomolecular Science, University of Science and Technology , Daejeon 34113, Korea.
  • Kim I; College of Pharmacy, Dongguk University , Goyang 10326, Korea.
  • Xu X; Personalized Genomic Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology , Daejeon 34141, Korea.
  • Harmalkar D; Functional Genomics, University of Science and Technology , Daejeon 34113, Korea.
  • Shin SA; College of Pharmacy, Dongguk University , Goyang 10326, Korea.
  • Kim M; College of Pharmacy, Dongguk University , Goyang 10326, Korea.
  • Kim BK; Personalized Genomic Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology , Daejeon 34141, Korea.
  • Park J; College of Pharmacy, Dongguk University , Goyang 10326, Korea.
  • Ku B; Personalized Genomic Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology , Daejeon 34141, Korea.
  • Oh S; College of Pharmacy, Dongguk University , Goyang 10326, Korea.
  • Won M; Disease Target Structure Research Center, Korea Research Institute of Bioscience and Biotechnology , Daejeon 34141, Korea.
  • Lee K; New Drug Development Center, Asan Medical Center , Seoul 05505, Korea.
J Med Chem ; 60(20): 8631-8646, 2017 10 26.
Article em En | MEDLINE | ID: mdl-28991459
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores Enzimáticos / Meta-Aminobenzoatos / Isoenzimas / Anilidas / Malato Desidrogenase / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2017 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores Enzimáticos / Meta-Aminobenzoatos / Isoenzimas / Anilidas / Malato Desidrogenase / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2017 Tipo de documento: Article País de publicação: Estados Unidos