Metal-based proteasomal deubiquitinase inhibitors as potential anticancer agents.

Chen, Xin; Yang, Qianqian; Xiao, Lu; Tang, Daolin; Dou, Q Ping; Liu, Jinbao

Chen, Xin; Yang, Qianqian; Xiao, Lu; Tang, Daolin; Dou, Q Ping; Liu, Jinbao.

Afiliação

Chen X; Protein Modification and Degradation Lab, School of Basic Medical Sciences, Affiliated Tumor Hospital of Guangzhou Medical University, Guangzhou, China.
Yang Q; Protein Modification and Degradation Lab, School of Basic Medical Sciences, Affiliated Tumor Hospital of Guangzhou Medical University, Guangzhou, China.
Xiao L; Protein Modification and Degradation Lab, School of Basic Medical Sciences, Affiliated Tumor Hospital of Guangzhou Medical University, Guangzhou, China.
Tang D; Protein Modification and Degradation Lab, School of Basic Medical Sciences, Affiliated Tumor Hospital of Guangzhou Medical University, Guangzhou, China.
Dou QP; Department of Surgery, University of Pittsburgh, Pittsburgh, PA, 15213, USA.
Liu J; Protein Modification and Degradation Lab, School of Basic Medical Sciences, Affiliated Tumor Hospital of Guangzhou Medical University, Guangzhou, China.

Cancer Metastasis Rev ; 36(4): 655-668, 2017 12.

Article em En | MEDLINE | ID: mdl-29039082

Assuntos

Antineoplásicos/farmacologia; Enzimas Desubiquitinantes/antagonistas & inibidores; Neoplasias/tratamento farmacológico; Neoplasias/enzimologia; Compostos Organometálicos/farmacologia; Inibidores de Proteassoma/farmacologia; Bibliotecas de Moléculas Pequenas/farmacologia; Animais; Enzimas Desubiquitinantes/metabolismo; Humanos

Palavras-chave

Cancer; DUB inhibitor; Deubiquitinase; Metal; Proteasome

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos Organometálicos / Bibliotecas de Moléculas Pequenas / Inibidores de Proteassoma / Enzimas Desubiquitinantes / Neoplasias / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: Cancer Metastasis Rev Assunto da revista: NEOPLASIAS Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China País de publicação: Holanda

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