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Prevalence of deleterious germline variants in risk genes including BRCA1/2 in consecutive ovarian cancer patients (AGO-TR-1).
Harter, Philipp; Hauke, Jan; Heitz, Florian; Reuss, Alexander; Kommoss, Stefan; Marmé, Frederik; Heimbach, André; Prieske, Katharina; Richters, Lisa; Burges, Alexander; Neidhardt, Guido; de Gregorio, Nikolaus; El-Balat, Ahmed; Hilpert, Felix; Meier, Werner; Kimmig, Rainer; Kast, Karin; Sehouli, Jalid; Baumann, Klaus; Jackisch, Christian; Park-Simon, Tjoung-Won; Hanker, Lars; Kröber, Sandra; Pfisterer, Jacobus; Gevensleben, Heidrun; Schnelzer, Andreas; Dietrich, Dimo; Neunhöffer, Tanja; Krockenberger, Mathias; Brucker, Sara Y; Nürnberg, Peter; Thiele, Holger; Altmüller, Janine; Lamla, Josefin; Elser, Gabriele; du Bois, Andreas; Hahnen, Eric; Schmutzler, Rita.
Afiliação
  • Harter P; Department of Gynecology & Gynecologic Oncology, Kliniken Essen-Mitte, Essen, Germany.
  • Hauke J; Center for Hereditary Breast and Ovarian Cancer, University Hospital Cologne, Medical Faculty, Cologne, Germany.
  • Heitz F; Center for Integrated Oncology (CIO), University Hospital Cologne, Medical Faculty, Cologne, Germany.
  • Reuss A; Department of Gynecology & Gynecologic Oncology, Kliniken Essen-Mitte, Essen, Germany.
  • Kommoss S; Coordinating Center for Clinical Trials, Philipps-University of Marburg, Marburg, Germany.
  • Marmé F; Department of Women's Health, Tübingen University Hospital, Tübingen, Germany.
  • Heimbach A; National Center for Tumor Disease/Department of Gynecology, University of Heidelberg, Heidelberg, Germany.
  • Prieske K; Institute of Human Genetics, University of Bonn, Bonn, Germany.
  • Richters L; Department of Gynecology and Gynecologic Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Burges A; Center for Hereditary Breast and Ovarian Cancer, University Hospital Cologne, Medical Faculty, Cologne, Germany.
  • Neidhardt G; Center for Integrated Oncology (CIO), University Hospital Cologne, Medical Faculty, Cologne, Germany.
  • de Gregorio N; Department of Gynecology, University Hospital Munich-Großhadern. Munich, Germany.
  • El-Balat A; Center for Hereditary Breast and Ovarian Cancer, University Hospital Cologne, Medical Faculty, Cologne, Germany.
  • Hilpert F; Center for Integrated Oncology (CIO), University Hospital Cologne, Medical Faculty, Cologne, Germany.
  • Meier W; Department of Gynecology, University of Ulm, Ulm, Germany.
  • Kimmig R; Department of Gynecology, University of Frankfurt, Frankfurt, Germany.
  • Kast K; Onkologisches Therapiezentrum, Krankenhaus Jerusalem, Hamburg, Germany/ Department of Gynecology, University of Kiel, Kiel, Germany.
  • Sehouli J; Department of Gynecology, University of Kiel, Kiel, Germany.
  • Baumann K; Department of Gynecology, Evangelisches Krankenhaus, Duesseldorf, Germany.
  • Jackisch C; Department of Gynecology, University of Essen, Essen, Germany.
  • Park-Simon TW; Department of Gynecology and Obstetrics, Medical Faculty and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
  • Hanker L; National Center for Tumor Diseases (NCT), Partner Site Dresden, Dresden, Germany.
  • Kröber S; German Cancer Consortium (DKTK), Dresden and German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Pfisterer J; Department of Gynecology and Gynecological Oncology, Charité, Campus Virchow, Berlin, Germany.
  • Gevensleben H; Department of Gynecology and Obstetrics, Klinikum Ludwigshafen, Ludwigshafen, Germany.
  • Schnelzer A; Department of Gynecology, Gynecologic Endocrinology & Oncology, Philipps-University Marburg, Marburg, Germany.
  • Dietrich D; Department of Gynecology and Obstetrics, Sana Klinikum, Offenbach, Germany.
  • Neunhöffer T; Department of Gynecology, Medizinische Hochschule Hannover, Hannover, Germany.
  • Krockenberger M; Department of Gynecology & Obstetrics, University Hospital Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.
  • Brucker SY; Center for Hereditary Breast and Ovarian Cancer, University Hospital Cologne, Medical Faculty, Cologne, Germany.
  • Nürnberg P; Center for Integrated Oncology (CIO), University Hospital Cologne, Medical Faculty, Cologne, Germany.
  • Thiele H; Center of Gynecological Oncology, Kiel, Germany.
  • Altmüller J; Institute of Pathology, University Hospital Bonn, Bonn, Germany.
  • Lamla J; Department of Gynecology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
  • Elser G; University Hospital Bonn, Department of Otolaryngology, Head and Neck Surgery, Bonn, Germany.
  • du Bois A; Department of Gynecology, Dr. Horst-Schmidt-Kliniken, Wiesbaden, Germany.
  • Hahnen E; Department of Gynecology, University of Würzburg, Würzburg, Germany.
  • Schmutzler R; Department of Women's Health, Tübingen University Hospital, Tübingen, Germany.
PLoS One ; 12(10): e0186043, 2017.
Article em En | MEDLINE | ID: mdl-29053726
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Mutação em Linhagem Germinativa / Genes BRCA1 / Predisposição Genética para Doença / Genes BRCA2 Tipo de estudo: Etiology_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Estados Unidos
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Mutação em Linhagem Germinativa / Genes BRCA1 / Predisposição Genética para Doença / Genes BRCA2 Tipo de estudo: Etiology_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Estados Unidos