[Effects of chlordemethyldiazepam on blood cortisol during surgical stress]. / Effetti del clordemetildiazepam sulla cortisolemia in corso di stress chirurgico.
Acta Biomed Ateneo Parmense
; 59(5-6): 199-204, 1988.
Article
em It
| MEDLINE
| ID: mdl-2908216
ABSTRACT
The pre-operative plasma cortisol levels in 16 male patients undergoing plastic-reconstructive surgery were studied. 8 patients received chlordesmethyldiazepam 0.1 mg/kg-1 i.v. (group C), 8 sodium thiopental 5 mg/kg-1 i.v. (group T) in anaesthesia induction. All patients were premedicated by diazepam 0.15 mg/kg-1 by mouth 90 min before anaesthesia induction and atropine 0.007 mg/kg-1 i.v. just before induction, and received succinylcholine 1 mg/kg-1 i.v. and an endotracheal tube for mechanically controlled ventilation. Anaesthesia maintenance was assured by isoflurane 0.5-2.5% in a N2O/O2 (2/1) gas mixture. Blood samples were collected from each patient at the following times 24 h before surgery (t0); 30 min after skin incision (t1); 30 min after extubation (t2). Significant variations of blood cortisol levels have not been shown.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Estresse Fisiológico
/
Procedimentos Cirúrgicos Operatórios
/
Ansiolíticos
/
Benzodiazepinas
/
Hidrocortisona
/
Nordazepam
/
Diazepam
Tipo de estudo:
Clinical_trials
Limite:
Adult
/
Humans
/
Male
/
Middle aged
Idioma:
It
Revista:
Acta Biomed Ateneo Parmense
Assunto da revista:
MEDICINA
Ano de publicação:
1988
Tipo de documento:
Article