Oligomer procyanidins (F2) repress HIF-1&#945; expression in human U87 glioma cells by inhibiting the EGFR/ AKT/mTOR and MAPK/ERK1/2 signaling pathways <i>in vitro</i> and <i>in vivo</i>.

Zheng, Hong-Li; Wang, Li-Hui; Sun, Bao-Shan; Li, Yi; Yang, Jing-Yu; Wu, Chun-Fu

Oligomer procyanidins (F2) repress HIF-1α expression in human U87 glioma cells by inhibiting the EGFR/ AKT/mTOR and MAPK/ERK1/2 signaling pathways in vitro and in vivo.

Zheng, Hong-Li; Wang, Li-Hui; Sun, Bao-Shan; Li, Yi; Yang, Jing-Yu; Wu, Chun-Fu.

Afiliação

Zheng HL; Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang, P.R. China.
Wang LH; Benxi Institute of Pharmaceutical Research, Shenyang Pharmaceutical University, Benxi, P.R. China.
Sun BS; Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang, P.R. China.
Li Y; Benxi Institute of Pharmaceutical Research, Shenyang Pharmaceutical University, Benxi, P.R. China.
Yang JY; Department of Enology, Shenyang Pharmaceutical University, Shenyang, P.R. China.
Wu CF; Viticultural and Enological Research Unit-National Institute for Agricultural and Veterinary Research, Dois Portos, Portugal.

Oncotarget ; 8(49): 85252-85262, 2017 Oct 17.

Article em En | MEDLINE | ID: mdl-29156717

Palavras-chave

F2; HIF-1α; U87 glioma cell; angiogenesis; invasion

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Oncotarget Ano de publicação: 2017 Tipo de documento: Article País de publicação: Estados Unidos

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