Halofuginone inhibits TGF-ß/BMP signaling and in combination with zoledronic acid enhances inhibition of breast cancer bone metastasis.

Juárez, Patricia; Fournier, Pierrick G J; Mohammad, Khalid S; McKenna, Ryan C; Davis, Holly W; Peng, Xiang H; Niewolna, Maria; Mauviel, Alain; Chirgwin, John M; Guise, Theresa A

Juárez, Patricia; Fournier, Pierrick G J; Mohammad, Khalid S; McKenna, Ryan C; Davis, Holly W; Peng, Xiang H; Niewolna, Maria; Mauviel, Alain; Chirgwin, John M; Guise, Theresa A.

Afiliação

Juárez P; Division of Endocrinology, Department of Medicine, Indiana University Purdue University at Indianapolis, Indiana, USA.
Fournier PGJ; Ensenada Center for Scientific Research and Higher Education, Ensenada, Mexico.
Mohammad KS; Division of Endocrinology, Department of Medicine, Indiana University Purdue University at Indianapolis, Indiana, USA.
McKenna RC; Ensenada Center for Scientific Research and Higher Education, Ensenada, Mexico.
Davis HW; Division of Endocrinology, Department of Medicine, Indiana University Purdue University at Indianapolis, Indiana, USA.
Peng XH; University of Virginia, Charlottesville, Virginia, USA.
Niewolna M; University of Virginia, Charlottesville, Virginia, USA.
Mauviel A; Division of Endocrinology, Department of Medicine, Indiana University Purdue University at Indianapolis, Indiana, USA.
Chirgwin JM; Division of Endocrinology, Department of Medicine, Indiana University Purdue University at Indianapolis, Indiana, USA.
Guise TA; Institute Curie, Orsay, France.

Oncotarget ; 8(49): 86447-86462, 2017 Oct 17.

Article em En | MEDLINE | ID: mdl-29156807

Palavras-chave

BMP; TGF-ß; bone metastases; halofuginone; zoledronic acid

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Oncotarget Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos

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