Detergent Insoluble Proteins and Inclusion Body-Like Structures Immunoreactive for PRKDC/DNA-PK/DNA-PKcs, FTL, NNT, and AIFM1 in the Amygdala of Cognitively Impaired Elderly Persons.

Gal, Jozsef; Chen, Jing; Katsumata, Yuriko; Fardo, David W; Wang, Wang-Xia; Artiushin, Sergey; Price, Douglas; Anderson, Sonya; Patel, Ela; Zhu, Haining; Nelson, Peter T

Gal, Jozsef; Chen, Jing; Katsumata, Yuriko; Fardo, David W; Wang, Wang-Xia; Artiushin, Sergey; Price, Douglas; Anderson, Sonya; Patel, Ela; Zhu, Haining; Nelson, Peter T.

Afiliação

Gal J; Department of Molecular and Cellular Biochemistry; Department of Biostatistics; Sanders-Brown Center on Aging; Department of Pathology, University of Kentucky, Lexington, Kentucky; and Research and Development, Lexington VA Medical Center, Lexington, Kentucky.
Chen J; Department of Molecular and Cellular Biochemistry; Department of Biostatistics; Sanders-Brown Center on Aging; Department of Pathology, University of Kentucky, Lexington, Kentucky; and Research and Development, Lexington VA Medical Center, Lexington, Kentucky.
Katsumata Y; Department of Molecular and Cellular Biochemistry; Department of Biostatistics; Sanders-Brown Center on Aging; Department of Pathology, University of Kentucky, Lexington, Kentucky; and Research and Development, Lexington VA Medical Center, Lexington, Kentucky.
Fardo DW; Department of Molecular and Cellular Biochemistry; Department of Biostatistics; Sanders-Brown Center on Aging; Department of Pathology, University of Kentucky, Lexington, Kentucky; and Research and Development, Lexington VA Medical Center, Lexington, Kentucky.
Wang WX; Department of Molecular and Cellular Biochemistry; Department of Biostatistics; Sanders-Brown Center on Aging; Department of Pathology, University of Kentucky, Lexington, Kentucky; and Research and Development, Lexington VA Medical Center, Lexington, Kentucky.
Artiushin S; Department of Molecular and Cellular Biochemistry; Department of Biostatistics; Sanders-Brown Center on Aging; Department of Pathology, University of Kentucky, Lexington, Kentucky; and Research and Development, Lexington VA Medical Center, Lexington, Kentucky.
Price D; Department of Molecular and Cellular Biochemistry; Department of Biostatistics; Sanders-Brown Center on Aging; Department of Pathology, University of Kentucky, Lexington, Kentucky; and Research and Development, Lexington VA Medical Center, Lexington, Kentucky.
Anderson S; Department of Molecular and Cellular Biochemistry; Department of Biostatistics; Sanders-Brown Center on Aging; Department of Pathology, University of Kentucky, Lexington, Kentucky; and Research and Development, Lexington VA Medical Center, Lexington, Kentucky.
Patel E; Department of Molecular and Cellular Biochemistry; Department of Biostatistics; Sanders-Brown Center on Aging; Department of Pathology, University of Kentucky, Lexington, Kentucky; and Research and Development, Lexington VA Medical Center, Lexington, Kentucky.
Zhu H; Department of Molecular and Cellular Biochemistry; Department of Biostatistics; Sanders-Brown Center on Aging; Department of Pathology, University of Kentucky, Lexington, Kentucky; and Research and Development, Lexington VA Medical Center, Lexington, Kentucky.
Nelson PT; Department of Molecular and Cellular Biochemistry; Department of Biostatistics; Sanders-Brown Center on Aging; Department of Pathology, University of Kentucky, Lexington, Kentucky; and Research and Development, Lexington VA Medical Center, Lexington, Kentucky.

J Neuropathol Exp Neurol ; 77(1): 21-39, 2018 Jan 01.

Article em En | MEDLINE | ID: mdl-29186589

Assuntos

Doença de Alzheimer/metabolismo; Tonsila do Cerebelo/metabolismo; Disfunção Cognitiva/metabolismo; Corpos de Inclusão/metabolismo; Idoso; Idoso de 80 Anos ou mais; Doença de Alzheimer/patologia; Tonsila do Cerebelo/patologia; Apoferritinas/metabolismo; Fator de Indução de Apoptose/metabolismo; Cromatografia Líquida; Disfunção Cognitiva/patologia; Proteína Quinase Ativada por DNA/metabolismo; Proteínas de Ligação a DNA/metabolismo; Humanos; Corpos de Inclusão/patologia; Proteínas Mitocondriais/metabolismo; NADP Trans-Hidrogenase Específica para A ou B/metabolismo; Proteínas Nucleares/metabolismo; Proteômica; Espectrometria de Massas em Tandem

Palavras-chave

ADSP; GWAS; LC-MS; Lewy; Phosphorylation; Proteomics; Tauopathy

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Corpos de Inclusão / Doença de Alzheimer / Disfunção Cognitiva / Tonsila do Cerebelo Tipo de estudo: Prognostic_studies Limite: Aged / Aged80 / Humans Idioma: En Revista: J Neuropathol Exp Neurol Ano de publicação: 2018 Tipo de documento: Article País de publicação: Reino Unido

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