A genome-wide DNA methylation analysis in peripheral blood from patients identifies risk loci associated with Graves' orbitopathy.

Xin, Z; Hua, L; Shi, T-T; Tuo, X; Yang, F-Y; Li, Y; Cao, X; Yang, J-K

Xin, Z; Hua, L; Shi, T-T; Tuo, X; Yang, F-Y; Li, Y; Cao, X; Yang, J-K.

Afiliação

Xin Z; Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China. xinz@medmail.com.cn.
Hua L; Department of Mathematics, School of Biomedical Engineering, Capital Medical University, Beijing, China.
Shi TT; Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Tuo X; Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Yang FY; Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Li Y; Physical Examination Department, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Cao X; Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Yang JK; Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China. jkyang@ccmu.edu.cn.

J Endocrinol Invest ; 41(6): 719-727, 2018 Jun.

Article em En | MEDLINE | ID: mdl-29190000

Assuntos

Biomarcadores/análise; Metilação de DNA; Genoma Humano; Oftalmopatia de Graves/sangue; Oftalmopatia de Graves/genética; Sequenciamento Completo do Genoma/métodos; Estudos de Casos e Controles; Seguimentos; Loci Gênicos; Humanos; Masculino; Pessoa de Meia-Idade; Prognóstico

Palavras-chave

Autoimmune; DNA methylation; Genome-wide; Graves' orbitopathy

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biomarcadores / Genoma Humano / Metilação de DNA / Oftalmopatia de Graves / Sequenciamento Completo do Genoma Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies Limite: Humans / Male / Middle aged Idioma: En Revista: J Endocrinol Invest Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China País de publicação: Itália

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