Lycopene mitigates ß-amyloid induced inflammatory response and inhibits NF-&#954;B signaling at the choroid plexus in early stages of Alzheimer's disease rats.

Liu, Chong-Bin; Wang, Rui; Yi, Yan-Feng; Gao, Zhen; Chen, Yi-Zhu

Lycopene mitigates ß-amyloid induced inflammatory response and inhibits NF-κB signaling at the choroid plexus in early stages of Alzheimer's disease rats.

Liu, Chong-Bin; Wang, Rui; Yi, Yan-Feng; Gao, Zhen; Chen, Yi-Zhu.

Afiliação

Liu CB; Department of Physiology, Basic Medical Science Building, Huzhou University, 313000, Huzhou, People's Republic of China; Department of Physiology, Basic Medical Science College, Wenzhou Medical University, 325035, Wenzhou, People's Republic of China. Electronic address: liuchongbin1972@126.com.
Wang R; Department of Physiology, Basic Medical Science Building, Huzhou University, 313000, Huzhou, People's Republic of China.
Yi YF; Department of Physiology, Basic Medical Science Building, Huzhou University, 313000, Huzhou, People's Republic of China.
Gao Z; Department of Physiology, Basic Medical Science Building, Huzhou University, 313000, Huzhou, People's Republic of China.
Chen YZ; Central Blood Station of Huzhou City, 313020, Huzhou, People's Republic of China. Electronic address: 13735180918@163.com.

J Nutr Biochem ; 53: 66-71, 2018 03.

Article em En | MEDLINE | ID: mdl-29195132

Assuntos

Doença de Alzheimer/tratamento farmacológico; Plexo Corióideo/efeitos dos fármacos; Licopeno/farmacologia; NF-kappa B/metabolismo; Doença de Alzheimer/metabolismo; Peptídeos beta-Amiloides/toxicidade; Precursor de Proteína beta-Amiloide/genética; Precursor de Proteína beta-Amiloide/metabolismo; Animais; Plexo Corióideo/metabolismo; Disfunção Cognitiva/tratamento farmacológico; Citocinas/metabolismo; Hipocampo/efeitos dos fármacos; Hipocampo/metabolismo; Masculino; NF-kappa B/genética; Fármacos Neuroprotetores/farmacologia; Fragmentos de Peptídeos/toxicidade; Ratos Wistar; Transdução de Sinais/efeitos dos fármacos; Receptor 4 Toll-Like/genética; Receptor 4 Toll-Like/metabolismo

Palavras-chave

Aß(142); Choroid plexus; Inflammation; Lycopene; NF-κB; Neuroprotection

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plexo Corióideo / NF-kappa B / Doença de Alzheimer / Licopeno Limite: Animals Idioma: En Revista: J Nutr Biochem Assunto da revista: BIOQUIMICA / CIENCIAS DA NUTRICAO Ano de publicação: 2018 Tipo de documento: Article País de publicação: Estados Unidos

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