A recombinant VSV-vectored MERS-CoV vaccine induces neutralizing antibody and T cell responses in rhesus monkeys after single dose immunization.

Liu, Renqiang; Wang, Jinliang; Shao, Yu; Wang, Xijun; Zhang, Huilei; Shuai, Lei; Ge, Jinying; Wen, Zhiyuan; Bu, Zhigao

Liu, Renqiang; Wang, Jinliang; Shao, Yu; Wang, Xijun; Zhang, Huilei; Shuai, Lei; Ge, Jinying; Wen, Zhiyuan; Bu, Zhigao.

Afiliação

Liu R; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, Heilongjiang Province, PR China.
Wang J; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, Heilongjiang Province, PR China.
Shao Y; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, Heilongjiang Province, PR China.
Wang X; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, Heilongjiang Province, PR China.
Zhang H; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, Heilongjiang Province, PR China.
Shuai L; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, Heilongjiang Province, PR China.
Ge J; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, Heilongjiang Province, PR China.
Wen Z; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, Heilongjiang Province, PR China. Electronic address: wenzhiyuan@caas.cn.
Bu Z; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, Heilongjiang Province, PR China. Electronic address: buzhigao@caas.cn.

Antiviral Res ; 150: 30-38, 2018 02.

Article em En | MEDLINE | ID: mdl-29246504

Assuntos

Anticorpos Antivirais/imunologia; Infecções por Coronavirus/prevenção & controle; Coronavírus da Síndrome Respiratória do Oriente Médio/imunologia; Linfócitos T/imunologia; Vacinas Sintéticas/imunologia; Vacinas Virais/imunologia; Animais; Anticorpos Neutralizantes/imunologia; Chlorocebus aethiops; Dipeptidil Peptidase 4/metabolismo; Modelos Animais de Doenças; Expressão Gênica; Genes Reporter; Vetores Genéticos/genética; Vetores Genéticos/imunologia; Humanos; Imunoglobulina G/imunologia; Macaca mulatta; Masculino; Linfócitos T/metabolismo; Vacinas Sintéticas/genética; Células Vero; Vacinas Virais/genética; Internalização do Vírus

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vacinas Virais / Vacinas Sintéticas / Linfócitos T / Infecções por Coronavirus / Coronavírus da Síndrome Respiratória do Oriente Médio / Anticorpos Antivirais Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Antiviral Res Ano de publicação: 2018 Tipo de documento: Article País de publicação: Holanda

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