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Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics.
Beaumont, Robin N; Warrington, Nicole M; Cavadino, Alana; Tyrrell, Jessica; Nodzenski, Michael; Horikoshi, Momoko; Geller, Frank; Myhre, Ronny; Richmond, Rebecca C; Paternoster, Lavinia; Bradfield, Jonathan P; Kreiner-Møller, Eskil; Huikari, Ville; Metrustry, Sarah; Lunetta, Kathryn L; Painter, Jodie N; Hottenga, Jouke-Jan; Allard, Catherine; Barton, Sheila J; Espinosa, Ana; Marsh, Julie A; Potter, Catherine; Zhang, Ge; Ang, Wei; Berry, Diane J; Bouchard, Luigi; Das, Shikta; Hakonarson, Hakon; Heikkinen, Jani; Helgeland, Øyvind; Hocher, Berthold; Hofman, Albert; Inskip, Hazel M; Jones, Samuel E; Kogevinas, Manolis; Lind, Penelope A; Marullo, Letizia; Medland, Sarah E; Murray, Anna; Murray, Jeffrey C; Njølstad, Pål R; Nohr, Ellen A; Reichetzeder, Christoph; Ring, Susan M; Ruth, Katherine S; Santa-Marina, Loreto; Scholtens, Denise M; Sebert, Sylvain; Sengpiel, Verena; Tuke, Marcus A.
Afiliação
  • Beaumont RN; Institute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter EX2 5DW, UK.
  • Warrington NM; Translational Research Institute, University of Queensland Diamantina Institute, Brisbane, QLD, Australia.
  • Cavadino A; Centre for Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
  • Tyrrell J; Institute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter EX2 5DW, UK.
  • Nodzenski M; European Centre for Environment and Human Health, University of Exeter, The Knowledge Spa, Truro TR1 3HD, UK.
  • Horikoshi M; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
  • Geller F; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.
  • Myhre R; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
  • Richmond RC; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
  • Paternoster L; Division of Epidemiology, Department of Genes and Environment, Norwegian Institute of Public Health, Oslo, Norway.
  • Bradfield JP; Medical Research Council Integrative Epidemiology Unit at the University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK.
  • Kreiner-Møller E; Population Health Science, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK.
  • Huikari V; The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands.
  • Metrustry S; Medical Research Council Integrative Epidemiology Unit at the University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK.
  • Lunetta KL; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Painter JN; Copenhagen Prospective Studies on Asthma in Childhood (COPSAC), Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Hottenga JJ; Danish Pediatric Asthma Center, Copenhagen University Hospital, Gentofte, Denmark.
  • Allard C; Institute of Health Sciences, University of Oulu, Oulu, Finland.
  • Barton SJ; Department of Twin Research, King's College London, St. Thomas' Hospital, London, UK.
  • Espinosa A; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
  • Marsh JA; Framingham Heart Study, Framingham, MA, USA.
  • Potter C; QIMR Berghofer Medical Research Institute, Royal Brisbane Hospital, Herston, QLD 4029, Australia.
  • Zhang G; EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands.
  • Ang W; Department of Biological Psychology, Vrije Universiteit Amsterdam, 1081 BT Amsterdam, The Netherlands.
  • Berry DJ; Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada.
  • Bouchard L; Medical Research Council Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK.
  • Das S; Pompeu Fabra University (UPF), Barcelona, Spain.
  • Hakonarson H; ISGlobal, Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain.
  • Heikkinen J; Division of Obstetrics and Gynaecology, The University of Western Australia, Perth, Australia.
  • Helgeland Ø; Institute of Genetic Medicine, Newcastle University, Central Parkway, Newcastle upon Tyne NE1 3BZ, UK.
  • Hocher B; Human Genetics Division, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • Hofman A; Center for Prevention of Preterm Birth, Perinatal Institute, Cincinnati Children's Hospital Medical Center, OH, USA.
  • Inskip HM; March of Dimes Prematurity Research Center Ohio Collaborative, Cincinnati, OH, USA.
  • Jones SE; Division of Obstetrics and Gynaecology, The University of Western Australia, Perth, Australia.
  • Kogevinas M; Population, Policy and Practice, UCL Great Ormond Street Institute of Child Health, University College London, London, UK.
  • Lind PA; Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada.
  • Marullo L; ECOGENE-21 and Lipid Clinic, Chicoutimi Hospital, Saguenay, QC, Canada.
  • Medland SE; Department of Biochemistry, Université de Sherbrooke, Sherbrooke, QC, Canada.
  • Murray A; Population, Policy and Practice, UCL Great Ormond Street Institute of Child Health, University College London, London, UK.
  • Njølstad PR; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Nohr EA; Division of Human Genetics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Reichetzeder C; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Ring SM; FIMM Institute for Molecular Medicine Finland, Helsinki University, Helsinki FI-00014, Finland.
  • Ruth KS; Department of Clinical Science, KG Jebsen Center for Diabetes Research, University of Bergen, Bergen, Norway.
  • Santa-Marina L; Department of Genetics and Bioinformatics, Domain of Health Data and Digitalisation, Institute of Public Health, Oslo, Norway.
  • Scholtens DM; The First Affiliated Hospital of Jinan University, Guangzhou 510630, China.
  • Sebert S; Institute of Nutritional Science, University of Potsdam, Potsdam, Germany.
  • Sengpiel V; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands.
  • Tuke MA; Medical Research Council Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK.
Hum Mol Genet ; 27(4): 742-756, 2018 02 15.
Article em En | MEDLINE | ID: mdl-29309628
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peso ao Nascer / Polimorfismo de Nucleotídeo Único / Estudo de Associação Genômica Ampla Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Female / Humans Idioma: En Revista: Hum Mol Genet Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Reino Unido
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peso ao Nascer / Polimorfismo de Nucleotídeo Único / Estudo de Associação Genômica Ampla Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Female / Humans Idioma: En Revista: Hum Mol Genet Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Reino Unido