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Recent advances and strategies in process and strain engineering for the production of butyric acid by microbial fermentation.
Luo, Hongzhen; Yang, Rongling; Zhao, Yuping; Wang, Zhaoyu; Liu, Zheng; Huang, Mengyu; Zeng, Qingwei.
Afiliação
  • Luo H; School of Life Science and Food Engineering, Huaiyin Institute of Technology, Huaian 223003, China. Electronic address: hzluo@hyit.edu.cn.
  • Yang R; School of Life Science and Food Engineering, Huaiyin Institute of Technology, Huaian 223003, China.
  • Zhao Y; School of Life Science and Food Engineering, Huaiyin Institute of Technology, Huaian 223003, China.
  • Wang Z; School of Life Science and Food Engineering, Huaiyin Institute of Technology, Huaian 223003, China.
  • Liu Z; School of Life Science and Food Engineering, Huaiyin Institute of Technology, Huaian 223003, China.
  • Huang M; School of Life Science and Food Engineering, Huaiyin Institute of Technology, Huaian 223003, China.
  • Zeng Q; School of Life Science and Food Engineering, Huaiyin Institute of Technology, Huaian 223003, China.
Bioresour Technol ; 253: 343-354, 2018 Apr.
Article em En | MEDLINE | ID: mdl-29329775
ABSTRACT
Butyric acid is an important platform chemical, which is widely used in the fields of food, pharmaceutical, energy, etc. Microbial fermentation as an alternative approach for butyric acid production is attracting great attention as it is an environmentally friendly bioprocessing. However, traditional fermentative butyric acid production is still not economically competitive compared to chemical synthesis route, due to the low titer, low productivity, and high production cost. Therefore, reduction of butyric acid production cost by utilization of alternative inexpensive feedstock, and improvement of butyric acid production and productivity has become an important target. Recently, several advanced strategies have been developed for enhanced butyric acid production, including bioprocess techniques and metabolic engineering methods. This review provides an overview of advances and strategies in process and strain engineering for butyric acid production by microbial fermentation. Additionally, future perspectives on improvement of butyric acid production are also proposed.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácido Butírico / Fermentação Idioma: En Revista: Bioresour Technol Assunto da revista: ENGENHARIA BIOMEDICA Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácido Butírico / Fermentação Idioma: En Revista: Bioresour Technol Assunto da revista: ENGENHARIA BIOMEDICA Ano de publicação: 2018 Tipo de documento: Article